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Collaborative Research: Cortical Processing Across Multiple Time and Space Scales

Contents

• Contact Information
• Funding Agency 
• Research Emphasis 
• Scales Examined 
• Biomedical, Biological &  Behavioral Areas
• Modeling Methods & Tools  
• Software Development 

Contact Information

Principal Investigator/Contact
David Cai
Courant Institute
Phone: (212) 998-3310
Fax: (212) 995-4121
Email: cai@cims.nyu.edu

Co-PIs and Collaborators
Gregor Kovacic
Rensselaer Polytechnic Institute

Louis Tao
New Jersey Institute of Technology 

Grant Number - 506396

Funding Agency

National Science Foundation (NSF)

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Research Emphasis

The project focuses on the physiological phenomena in the primary visual cortex. The primary visual cortex (V1) is a complex integrated circuit that performs fundamental tasks in processing of visual information by the brain. The central theme of this proposal is to investigate how the neuronal responses of V1, ranging from feature selectivity to illusory perception, are induced and influenced by network components at many scales.

The software developed will form a general simulation platform of a hierarchical computational V1 model that is validated for many well-characterized physiological processes and is capable of possessing predictive power for functions emerging out of its many scales. 

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Scales Examined 

Time Scales

• Microsecond (μs)
• Millisecond (ms)
• Second (s)
• Minutes

Biological Scales

• Sub-Cellular
• Cellular
• Multi-Cellular Systems
• Tissue

Length Scales 

• Micrometer (μm)
• Millimeter (mm)
• Centimeter (cm)
• Ten centimeter

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Biomedical, Biological and Behavioral (BBB) Areas and Percent Focus

50% - Physiological phenomena in primary visual cortex.

Modeling Methods and Tools (MMT)Areas and Percent Focus

50% - Fast algorithms, statistical formalisms for computational scale-up and effective dynamics.   

Software Development