Protein-Protein Interaction Information
Interaction: HDRi9
| Region | Residue | Interacting Mechanism | ||
| SIX3_MOUSE | homeodomain | 207-266 | Enhance Pax-6-mediated transactivation upon coexpression. Demonstrates that divergent homeodomains interact with Pax6 in vitro and in vivo. Pax6 homeodomain and paired-domain function as protein-protein interaction domain. | |
| P26630 | homeodomain | 229-288 |
Proteins
| SIX3_MOUSE | ||
| Protein HDR ID | HDRp509 | |
| Entrez | Six3 - sine oculis-related homeobox 3 homolog (Drosophila) | |
| P26630 | ||
| Protein HDR ID | HDRp545 | |
| Entrez | pax6a - paired box gene 6a | |
Reference
| Title | Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins. |
| First Author | Mikkola I |
| Journal | J. Biol. Chem. 276: 4109-18, 2001 |
| BIND | 266424 (BOND log-in process is required) |
  
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