Septo-optic dysplasia (SOD) is a rare disorder characterized by abnormal development of the optic disk, pituitary deficiencies, and often agenesis (absence) of the septum pellucidum (the part of the brain that separates the anterior horns or the lateral ventricles of the brain). Symptoms may include blindness in one or both eyes, pupil dilation in response to light, nystagmus (a rapid, involuntary to-and-fro movement of the eyes), inward and outward deviation of the eyes, hypotonia (low muscle tone), and hormonal problems. Seizures may also occur. In a few cases, jaundice (prolonged yellow skin discoloration) may occur at birth. Intellectual problems vary in severity among individuals. While some children with SOD have normal intelligence, others have learning disabilities and mental retardation. Most, however, are developmentally delayed due to vision impairment or neurological problems.
March of Dimes Foundation 1275 Mamaroneck Avenue White Plains, NY 10605 askus@marchofdimes.com http://www.marchofdimes.com Tel: 914-428-7100 888-MODIMES (663-4637) Fax: 914-428-8203 |
National Organization for Rare Disorders (NORD) P.O. Box 1968 (55 Kenosia Avenue) Danbury, CT 06813-1968 orphan@rarediseases.org http://www.rarediseases.org Tel: 203-744-0100 Voice Mail 800-999-NORD (6673) Fax: 203-798-2291 |
National Eye Institute (NEI) National Institutes of Health, DHHS 31 Center Drive, Rm. 6A32 MSC 2510 Bethesda, MD 20892-2510 2020@nei.nih.gov http://www.nei.nih.gov Tel: 301-496-5248 |
National Institute of Diabetes and Digestive
and Kidney Diseases (NIDDK) National Institutes of Health, DHHS 31 Center Drive, Rm. 9A06 MSC 2560 Bethesda, MD 20892-2560 http://www.niddk.nih.gov Tel: 301-496-3583 TTY: 866-569-1162 |
FOCUS Families 228 E. Palomino Court Gilbert, AZ 85296 support_families@focusfamilies.org http://www.focusfamilies.org Tel: 866-FOCUS-50 (866-362-8750) Fax: 866-362-8750 |
Magic Foundation [Growth Disorders] 6645 West North Avenue Oak Park, IL 60302 http://www.magicfoundation.org Tel: 708-383-0808 800-3-MAGIC3 (362-4423) Fax: 708-383-0899 |
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Last updated August 01, 2008