Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne - Full Text View

Sponsored by:	Shaheed Beheshti Medical University
Information provided by:	Shaheed Beheshti Medical University
ClinicalTrials.gov Identifier:	NCT00416585

Purpose

serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne

Condition	Intervention	Phase
Acne	Drug: isotretinoin (Roaccutane)	Phase I

MedlinePlus related topics: Acne

Drug Information available for: Isotretinoin Calcium gluconate Vitamin D Ergocalciferol

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Dose Comparison, Single Group Assignment, Safety/Efficacy Study
Official Title:	Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment

Further study details as provided by Shaheed Beheshti Medical University:

Primary Outcome Measures:

serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray before the treatment

Secondary Outcome Measures:

serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray after the treatment

Estimated Enrollment:	30
Study Start Date:	October 2005
Estimated Study Completion Date:	November 2006

Detailed Description:

few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

sever acne

Exclusion Criteria:

renal disorders
gastrointestinal disorders
skeletal disorders
endocrine disorders
drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids, tetracyclines

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00416585

Locations

Iran, Islamic Republic of
Shaheed Beheshti Medical University, Skin research center
Tehran, Iran, Islamic Republic of, 198994148

Sponsors and Collaborators

Shaheed Beheshti Medical University

Investigators

Study Chair:	parviz toossi, md	Skin Research Center
Principal Investigator:	Hamideh Moravvej, md	Skin Research Center
Principal Investigator:	Nahid Mohtasham, md	Skin Research Center

More Information

Study ID Numbers:	src-hmnm-1385
Study First Received:	December 27, 2006
Last Updated:	January 22, 2008
ClinicalTrials.gov Identifier:	NCT00416585
Health Authority:	Iran: Ministry of Health

Keywords provided by Shaheed Beheshti Medical University:

acne
isotretinoin
calcium. vitamin D

Study placed in the following topic categories:

Calcium, Dietary
Exanthema
Vitamin D
Facial Dermatoses
Facies

Skin Diseases
Isotretinoin
Ergocalciferols
Sebaceous Gland Diseases
Acne Vulgaris

Additional relevant MeSH terms:

Acneiform Eruptions
Therapeutic Uses
Growth Substances
Vitamins
Physiological Effects of Drugs

Bone Density Conservation Agents
Micronutrients
Dermatologic Agents
Pharmacologic Actions

ClinicalTrials.gov processed this record on January 16, 2009