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Table of Contents
Larger Cover
November 2002
Volume 15, Issue 11
Pages 1331-1487
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For Selected Articles:
PERSPECTIVE
Acetaldehyde in Mainstream Tobacco Smoke: Formation and Occurrence in Smoke and Bioavailability in the Smoker
Jeffrey I. Seeman,*
†
Michael Dixon,*
‡
and Hans-Jürgen Haussmann*
§
pp 1331–1350
Publication Date (Web):
November 18, 2002
(Perspective)
DOI:
10.1021/tx020069f
Abstract
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[248K]
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Figure 1
COMMUNICATIONS
Metabolic Profiling of the Effects of
d
-Galactosamine in Liver Spheroids Using
1
H NMR and MAS-NMR Spectroscopy
Mary E. Bollard,*
†
Jinsheng Xu,
‡
Wendy Purcell,
‡
Julian L. Griffin,
†
Christopher Quirk,
§
Elaine Holmes,
†
and Jeremy K. Nicholson
†
pp 1351–1359
Publication Date (Web):
October 19, 2002
(Communication)
DOI:
10.1021/tx025571e
Abstract
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[251K]
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Figure 1
ARTICLES
Biological Monitoring of 2,4,5-Trichlorophenol (I): Preparation of Antibodies and Development of an Immunoassay Using Theoretical Models
Mikaela Nichkova, Roger Galve, and M.-Pilar Marco*
pp 1360–1370
Publication Date (Web):
October 10, 2002
(Article)
DOI:
10.1021/tx025555h
Abstract
Addition/Correction
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[210K]
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Figure 1
Biological Monitoring of 2,4,5-Trichlorophenol (II): Evaluation of an Enzyme-Linked Immunosorbent Assay for the Analysis of Water, Urine, and Serum Samples
Mikaela Nichkova, Roger Galve, and M.-Pilar Marco*
pp 1371–1379
Publication Date (Web):
October 10, 2002
(Article)
DOI:
10.1021/tx025556+
Abstract
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[133K]
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Figure 1
Analytical Reproducibility in
1
H NMR-Based Metabonomic Urinalysis
Hector C. Keun,*
†
Timothy M. D. Ebbels,
†
Henrik Antti,
†
Mary E. Bollard,
†
Olaf Beckonert,
†
Götz Schlotterbeck,
‡
Hans Senn,
‡
Urs Niederhauser,
‡
Elaine Holmes,
†
John C. Lindon,
†
and Jeremy K. Nicholson
†
pp 1380–1386
Publication Date (Web):
October 17, 2002
(Article)
DOI:
10.1021/tx0255774
Abstract
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[137K]
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Figure 1
Mass Spectral Characterization of Dichloroacetic Acid-Modified Human Glutathione Transferase Zeta
Wayne B. Anderson,
†
Daniel C. Liebler,
‡
Philip G. Board,
§
and M. W. Anders*
†
pp 1387–1397
Publication Date (Web):
September 27, 2002
(Article)
DOI:
10.1021/tx025553x
Abstract
|
Supporting Info
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[164K]
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Figure 1
Relative Toxicities of DNA Cross-Links and Monoadducts: New Insights from Studies of Decarbamoyl Mitomycin C and Mitomycin C
Yolanda Palom,
†
‡
Gopinatha Suresh Kumar,
†
§
Li-Qian Tang,
Manuel M. Paz,
†
#
Steven M. Musser,
Sara Rockwell,
and Maria Tomasz*
†
pp 1398–1406
Publication Date (Web):
October 08, 2002
(Article)
DOI:
10.1021/tx020044g
Abstract
|
Supporting Info
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[185K]
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Figure 1
Substrate Routes to the Buried Active Site May Vary among Cytochromes P450: Mutagenesis of the F−G Region in P450 2B1
†
Emily E. Scott,* You Qun He, and James R. Halpert
pp 1407–1413
Publication Date (Web):
October 09, 2002
(Article)
DOI:
10.1021/tx020057u
Abstract
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[115K]
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Figure 1
Microsomal Oxidation of Tribromoethylene and Reactions of Tribromoethylene Oxide
Tadao Yoshioka, Joel A. Krauser, and F. Peter Guengerich*
pp 1414–1420
Publication Date (Web):
October 10, 2002
(Article)
DOI:
10.1021/tx020047t
Abstract
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[121K]
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Figure 1
Species Differences in the in Vitro Metabolic Activation of the Hepatotoxic Pyrrolizidine Alkaloid Clivorine
Ge Lin,*
†
Yan-Yan Cui,
†
Xiao-Quan Liu,
†
‡
and Zhen-Tao Wang
§
pp 1421–1428
Publication Date (Web):
October 10, 2002
(Article)
DOI:
10.1021/tx0255370
Abstract
Full Text HTML
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[122K]
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Figure 1
Molecular Modeling of Four Stereoisomers of the Major B[
a
]PDE Adduct (at N
2
-dG) in Five Cases Where the Structure Is Known from NMR Studies: Molecular Modeling Is Consistent with NMR Results
Chiu Hong Lee, Sushil Chandani, and Edward L. Loechler*
pp 1429–1444
Publication Date (Web):
October 12, 2002
(Article)
DOI:
10.1021/tx0200257
Abstract
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[509K]
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Figure 1
Covalent Modification of Amino Acid Nucleophiles by the Lipid Peroxidation Products 4-Hydroxy-2-nonenal and 4-Oxo-2-nonenal
†
Jonathan A. Doorn and Dennis R. Petersen*
pp 1445–1450
Publication Date (Web):
October 05, 2002
(Article)
DOI:
10.1021/tx025590o
Abstract
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[95K]
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Figure 1
Antioxidant Balance and Free Radical Generation in Vitamin E-Deficient Mice after Dermal Exposure to Cumene Hydroperoxide
A. A. Shvedova,*
†
E. R. Kisin,
†
A. R. Murray,
‡
C. Kommineni,
†
V. Castranova,
†
R. P. Mason,
§
M. B. Kadiiska,
§
and M. R. Gunther
‡
pp 1451–1459
Publication Date (Web):
October 18, 2002
(Article)
DOI:
10.1021/tx0200313
Abstract
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[150K]
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Figure 1
Synthesis of Oligonucleotides and Thermal Stability of Duplexes Containing the β-C-Nucleoside Analogue of Fapy·dG
Michael O. Delaney
†
and Marc M. Greenberg*
‡
pp 1460–1465
Publication Date (Web):
October 17, 2002
(Article)
DOI:
10.1021/tx025588x
Abstract
|
Supporting Info
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[112K]
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Figure 1
Biliary Excretion of [(GS)
2
AsSe]
-
after Intravenous Injection of Rabbits with Arsenite and Selenate
Jürgen Gailer,* Graham N. George,
†
Ingrid J. Pickering,
†
Roger C. Prince,
‡
Husam S. Younis,
§
and J. J. Winzerling
pp 1466–1471
Publication Date (Web):
October 24, 2002
(Article)
DOI:
10.1021/tx025538s
Abstract
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[75K]
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Figure 1
Metabolic Response of Normal and Malignant Tissue to Acute and Chronic Methionine Stress in Athymic Mice Bearing Human Glial Tumor Xenografts
Demetrius M. Kokkinakis,* Jacquellyn B. Wick, and Qing Xian Zhou
pp 1472–1479
Publication Date (Web):
October 24, 2002
(Article)
DOI:
10.1021/tx020033n
Abstract
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[135K]
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Figure 1
Enantioselective Covalent Binding of 2-Phenylpropionic Acid to Protein in Vitro in Rat Hepatocytes
†
Chunze Li, Leslie Z. Benet,* and Mark P. Grillo
‡
pp 1480–1487
Publication Date (Web):
October 31, 2002
(Article)
DOI:
10.1021/tx025600l
Abstract
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[154K]
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Figure 1
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