The Genetic Signatures of Noncoding RNAs
John S. Mattick outlines the emerging evidence for non–protein-coding RNA involvement in key molecular genetic phenomena and in specific functions and phenotypes.
John S. Mattick outlines the emerging evidence for non–protein-coding RNA involvement in key molecular genetic phenomena and in specific functions and phenotypes.
The authors show that an evolutionarily conserved secreted protein, Neural Lazarillo (NLaz), is induced in response to stress signals in fruit flies, and that it is required for metabolic regulation.
After evaluating several potential time limiting steps, the authors show that the RNA polymerase type is an important early factor contributing to the divergent retrotransposition kinetics between LINEs and SINEs.
The authors propose a method for multiple testing correction called SLIDE: a Sliding-window approach for Locally Inter-correlated markers with asymptotic Distribution Errors corrected.
PLoS Biology; PLoS Medicine; PLoS Computational Biology; PLoS Pathogens; PLoS ONE; PLoS Neglected Tropical Diseases
PLoS Biology; PLoS Medicine; PLoS Computational Biology; PLoS ONE; PLoS Neglected Tropical Diseases
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