Canagarajah, B., Hummer, G., Prinz, W. and Hurley, J. H.
Dynamics of Cholesterol Exchange in the OSBP-Related Protein Family. J. Mol. Biol.
378
, 737-748 (2008).
Hurley, J. H. ESCRT Complexes and the Biogenesis of Multivesicular Bodies. Curr. Opin. Cell Biol. 20, 4-11 (2008).
Hurley, J. H. and Yang, D. MIT Domainia. Dev. Cell. 14, 6-8 (2008).
Bonifacino, J. S. and Hurley, J. H. Retromer. Curr. Opin. Cell Biol. 20, 427-436 (2008).
Im, Y. J. and Hurley, J. H. Integrated Structural Model and Membrane Targeting Mechanism of the Human ESCRT-II Complex Dev. Cell. 14, 902-913 (2008).
Yang, D., Rismanchi, N., Renvoise, B., Lippincott-Schwartz, J., Blackstone, C. and Hurley. J. H. Structural Basis for Midbody Targeting of Spastin by the ESCRT-III Protein CHMP1B. Nat. Struct. Mol. Biol 15, 1278-1286 (2008).
Lee, H., Elia, N., Ghirlando, R., Lippincott-Schwartz, J. and Hurley. J. H. Midbody Targeting of the ESCRT Machinery by a Non-Canonical Coiled-Coil in CEP55. Science 322, 576-580 (2008).Lindwasser OW, Smith WJ, Chaudhuri R, Yang P, Hurley JH, Bonifacino JS A Diacidic Motif in HIV-1 Nef is a Novel Determinant of Binding to AP2.
J Virol, 2007. [
Full Text/Abstract]
Munshi UM, Kim J, Nagashima K, Hurley JH, Freed EO An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains. J Biol Chem(282): 3847-55, 2007. [Full Text/Abstract]
Fujii K, Hurley JH, Freed EO Beyond Tsg101: the role of Alix in ''ESCRTing'' HIV-1. Nat Rev Microbiol(5): 912-6, 2007. [Full Text/Abstract]
Chaudhuri R, Lindwasser OW, Smith WJ, Hurley JH, Bonifacino JS Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor. J Virol(81): 3877-90, 2007. [Full Text/Abstract]
Hierro A, Rojas AL, Rojas R, Murthy N, Effantin G, Kajava AV, Steven AC, Bonifacino JS, Hurley JH Functional architecture of the retromer cargo-recognition complex. Nature(449): 1063-7, 2007. [Full Text/Abstract]
Kostelansky MS, Schluter C, Tam YY, Lee S, Ghirlando R, Beach B, Conibear E, Hurley JH Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell(129): 485-98, 2007. [Full Text/Abstract]
Lee S, Joshi A, Nagashima K, Freed EO, Hurley JH Structural basis for viral late-domain binding to Alix. Nat Struct Mol Biol(14): 194-9, 2007. [Full Text/Abstract]
Prag G, Watson H, Kim YC, Beach BM, Ghirlando R, Hummer G, Bonifacino JS, Hurley JH The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting. Dev Cell(12): 973-86, 2007. [Full Text/Abstract]
Leonard TA, Hurley JH Two kinase family dramas. Cell(129): 1037-8, 2007. [Full Text/Abstract]
Hurley JH Membrane binding domains. Biochim Biophys Acta (1761): 805-11, 2006. [Full Text/Abstract]
Raychaudhuri S, Im YJ, Hurley JH, Prinz WA Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein-related proteins and phosphoinositides. J Cell Biol (173): 107-19, 2006. [Full Text/Abstract]
Wang H, Yang C, Leskow FC, Sun J, Canagarajah B, Hurley JH, Kazanietz MG Phospholipase Cgamma/diacylglycerol-dependent activation of beta2-chimaerin restricts EGF-induced Rac signaling. EMBO J (25): 2062-74, 2006. [Full Text/Abstract]
Kostelansky MS, Sun J, Lee S, Kim J, Ghirlando R, Hierro A, Emr SD, Hurley JH Structural and functional organization of the ESCRT-I trafficking complex. Cell (125): 113-26, 2006. [Full Text/Abstract]
Lee S, Tsai YC, Mattera R, Smith WJ, Kostelansky MS, Weissman AM, Bonifacino JS, Hurley JH Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Nat Struct Mol Biol (13): 264-71, 2006. [Full Text/Abstract]
Hurley JH, Emr SD The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annu Rev Biophys Biomol Struct (35): 277-98, 2006. [Full Text/Abstract]
Shi H, Rojas R, Bonifacino JS, Hurley JH The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nat Struct Mol Biol (13): 540-8, 2006. [Full Text/Abstract]
Hurley JH, Lee S, Prag G Ubiquitin-binding domains. Biochem J (399): 361-72, 2006. [Full Text/Abstract]
Hierro A, Kim J, Hurley JH Polycistronic expression and purification of the ESCRT-II endosomal trafficking complex. Methods Enzymol (403): 322-32, 2005. [Full Text/Abstract]
Miller GJ, Wilson MP, Majerus PW, Hurley JH Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol Cell (18): 201-12, 2005. [Full Text/Abstract]
Kim J, Sitaraman S, Hierro A, Beach BM, Odorizzi G, Hurley JH Structural basis for endosomal targeting by the bro1 domain. Dev Cell (8): 937-47, 2005. [Full Text/Abstract]
Im YJ, Raychaudhuri S, Prinz WA, Hurley JH Structural mechanism for sterol sensing and transport by OSBP-related proteins. Nature (437): 154-8, 2005. [Full Text/Abstract]
Prag G, Lee S, Mattera R, Arighi CN, Beach BM, Bonifacino JS, Hurley JH Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins. Proc Natl Acad Sci U S A (102): 2334-9, 2005. [Full Text/Abstract]
Chi Y Zhou B Wang WQ Chung SK Kwon YU Ahn YH Chang YT Tsujishita Y Hurley JH Zhang ZY Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatases SPsynaptojanin and SHIP2. J Biol Chem , 2004. [Full Text/Abstract]
Miller GJ, Hurley JH Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase. Mol Cell (15): 703-11, 2004. [Full Text/Abstract]
Canagarajah B, Leskow FC, Ho JY, Mischak H, Saidi LF, Kazanietz MG, Hurley JH Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell (119): 407-18, 2004. [Full Text/Abstract]
Hickenbottom SJ Kimmel AR Londos C Hurley JH Structure of a lipid droplet protein; the PAT family member TIP47. Structure (Camb) (12): 1199-207, 2004. [Full Text/Abstract]
Hierro A, Sun J, Rusnak AS, Kim J, Prag G, Emr SD, Hurley JH Structure of the ESCRT-II endosomal trafficking complex. Nature (431): 221-5, 2004. [Full Text/Abstract]
Fritz TA, Hurley JH, Trinh LB, Shiloach J, Tabak LA The beginnings of mucin biosynthesis: the crystal structure of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-T1. Proc Natl Acad Sci U S A (101): 15307-12, 2004. [Full Text/Abstract]
Corbin JD Blount MA Weeks JL 2nd Beasley A Kuhn KP Ho YS Saidi LF Hurley JH Kotera J Francis SH 3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP. Mol Pharmacol (63): 1364-72, 2003. [Full Text/Abstract]
Shih SC Prag G Francis SA Sutanto MA Hurley JH Hicke L A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J (22): 1273-81, 2003. [Full Text/Abstract]
Zhang G Hurley JH Crystallization of the protein kinase Cdelta C1B domain. Methods Mol Biol (233): 299-304, 2003. [Full Text/Abstract]
Hurley JH GAF domains: cyclic nucleotides come full circle. Sci STKE (2003): PE1, 2003. [Full Text/Abstract]
Hurley JH Leucine in the sky with diamonds. Structure (Camb) (11): 1192-3, 2003. [Full Text/Abstract]
Trievel RC Flynn EM Houtz RL Hurley JH Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT. Nat Struct Biol (10): 545-52, 2003. [Full Text/Abstract]
Prag G Misra S Jones EA Ghirlando R Davies BA Horazdovsky BF Hurley JH Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell (113): 609-20, 2003. [Full Text/Abstract]
Hurley JH Membrane proteins: adapting to life at the interface. Chem Biol (10): 2-3, 2003. [Full Text/Abstract]
Miller GJ Mattera R Bonifacino JS Hurley JH Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3. Nat Struct Biol (10): 599-606, 2003. [Full Text/Abstract]
Hurley JH Structural analysis of protein kinase C: an introduction. Methods Mol Biol (233): 289-90, 2003. [Full Text/Abstract]
Suer S Misra S Saidi LF Hurley JH Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor. Proc Natl Acad Sci U S A (100): 4451-6, 2003. [Full Text/Abstract]
Hurley JH Wendland B Endocytosis: driving membranes around the bend. Cell (111): 143-6, 2002. [Full Text/Abstract]
Aasland R Abrams C Ampe C Ball LJ Bedford MT Cesareni G Gimona M Hurley JH Jarchau T Lehto VP Lemmon MA Linding R Mayer BJ Nagai M Sudol M Walter U Winder SJ Normalization of nomenclature for peptide motifs as ligands of modular protein domains. FEBS Lett (513): 141-4, 2002. [Full Text/Abstract]
Kato Y Misra S Puertollano R Hurley JH Bonifacino JS Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. Nat Struct Biol (9): 532-6, 2002. [Full Text/Abstract]
Misra S Puertollano R Kato Y Bonifacino JS Hurley JH Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature (415): 933-7, 2002. [Full Text/Abstract]
Hurley JH Anderson DE Beach B Canagarajah B Ho YS Jones E Miller G Misra S Pearson M Saidi L Suer S Trievel R Tsujishita Y Structural genomics and signaling domains. Trends Biochem Sci (27): 48-53, 2002. [Full Text/Abstract]
Trievel RC Beach BM Dirk LM Houtz RL Hurley JH Structure and catalytic mechanism of a SET domain protein methyltransferase. Cell (111): 91-103, 2002. [Full Text/Abstract]
Misra S Miller GJ Hurley JH Recognizing phosphatidylinositol 3-phosphate. Cell (107): 559-62, 2001. [Full Text/Abstract]
Tsujishita Y Guo S Stolz LE York JD Hurley JH Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. Cell (105): 379-89, 2001. [Full Text/Abstract]
Hurley JH Meyer T Subcellular targeting by membrane lipids. Curr Opin Cell Biol (13): 146-52, 2001. [Full Text/Abstract]
Hurley JH Tsujishita Y Pearson MA Floundering about at cell membranes: a structural view of phospholipid signaling. Curr Opin Struct Biol (10): 737-43, 2000. [Full Text/Abstract]
Hurley JH Misra S Signaling and subcellular targeting by membrane-binding domains. Annu Rev Biophys Biomol Struct (29): 49-79, 2000. [Full Text/Abstract]