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diethylstilbestrol DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | diethylstilbestrol dipropionate diethylstilbestrolum Sinestrol stilboestrol dipropionate | | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | US brand names: | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | Acnestrol Cyren A Deladumone Diastyl Domestrol Estrobene Estrobene Estrosyn Fonatol Makarol Milestrol Milestrol Neo-Oestronol I Oestrogenine Oestromenin Oestromon Palestrol stilbestrol Stilbetin Stilboestroform Stilboestrol Synestrin Synthoestrin Vagestrol | | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand names: | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | Antigestil Apstil Boestrol Bufon Distilbene Distilbene Estrogenine Estromenin Grafestrol Microest Oestromensyl Serral Sexocretin Sibol Stilboefral Stilkap | | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | DES | | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure names: | ![](https://webarchive.library.unt.edu/web/20090114224200im_/http://www.cancer.gov/images/spacer.gif) | - (E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol
- 3,4-bis(p-hydroxyphenyl)-3-hexene
- 4,4'-dihydroxy-alpha,beta-diethylstilbene
- alpha,alpha'-diethylstilbenediol
- trans-bis-(hydroxy-4-phenyl)-3,4 hexene-3
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