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samarium Sm 153 lexidronam pentasodium The pentasodium salt of samarium Sm 135 lexidronam, a therapeutic agent consisting of a medium energy beta- and gamma-emitting radioisotope, samarium Sm 135, and a teraphosphonate chelator, ethylenediaminetetramethylene phosphonic acid (EDTMP). The chelator moiety of samarium Sm 153 lexidronam associates with hydroxyapatite crystals concentrated in areas of bone turnover, thereby selectively delivering samarium Sm 153-mediated cytotoxic radiation to osteoblastic bone metastases. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonyms: | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) | samarium Sm 153 lexidronam Samarium-153 EDTMP Sm 153 lexidronam pentasodium Sm-153 EDTMP | | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) | Quadramet | | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) | Abbreviations: | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) | 153Sm-EDTMP Sm-153 EDTMP | | ![](https://webarchive.library.unt.edu/web/20090115022920im_/http://www.cancer.gov/images/spacer.gif) |
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