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testolactone A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms: | | Fludestrin therapeutic testolactone | | | US brand name: | | Teslac | | | Abbreviation: | | TL | | | Code name: | | SQ-9538 | | | Chemical structure names: | | - 1,2,3,4,4a,4b,7,9,10,10a-decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic acid delta-lactone
- 13-hydroxy-3-0x0-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone
- 17alpha-oxo-D-homo-1,4-androstadiene-3,17-dione
- 1-dehydrotestololactone
- delta-1-testololactone
- D-homo-17a-oxaandrosta-1,4-diene-3,17-dione
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