![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) |
|
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif)
prednisolone A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif)
Synonyms: | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | delta(1)hydrocortisone delta1-dehydro-hydrocortisone deltahydrocortisone metacortandralone | | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | US brand names: | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | Cortalone Delta-Cortef Hydeltra Hydeltrasol Meti-derm Prelone | | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand names: | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | Adnisolone Aprednislon Capsoid Cortisolone Dacortin H Decaprednil Decortin H Decortin H Delta- Cortef Deltacortril Delta-Diona Delta-Phoricol Deltasolone Deltidrosol Dhasolone Di-Adreson-F Dontisolon D Estilsona Fisopred Frisolona Gupisone Hostacortin H Klismacort Kuhlprednon Lenisolone Lepi-Cortinolo Linola-H N Linola-H-Fett N Longiprednil Meticortelone Opredsone Panafcortelone Precortisyl Pred-Clysma Predeltilone Predni-Coelin Prednicortelone Predni-Helvacort Prenilone | | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | Abbreviation: | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | PRDL | | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | Chemical structure names: | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) | - (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
- 1,2-dehydrohydrocortisone
| | ![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) |
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif)
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/gray_spacer.gif)
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif)
|
![](https://webarchive.library.unt.edu/web/20090114232406im_/http://www.cancer.gov/images/spacer.gif) |