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famotidine A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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US brand names: | ![](https://webarchive.library.unt.edu/web/20090114221131im_/http://www.cancer.gov/images/spacer.gif) | Pepcid Pepcid AC | | ![](https://webarchive.library.unt.edu/web/20090114221131im_/http://www.cancer.gov/images/spacer.gif) |
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