KATHY:Cognitive-Behavioural Therapy for Hypochondriasis - Full Text View

Sponsors and Collaborators:	Copenhagen Trial Unit, Center for Clinical Intervention Research Bispebjerg Hospital
Information provided by:	Copenhagen Trial Unit, Center for Clinical Intervention Research
ClinicalTrials.gov Identifier:	NCT00208247

Purpose

The purpose of this study was to examined if psychotherapy is an effecitive treatment for hypochondriasis.

Condition	Intervention	Phase
Hypochondriasis	Behavioral: Cognitive behavioral psychotherapy	Phase II

MedlinePlus related topics: Anxiety

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Single Blind, Active Control, Crossover Assignment, Efficacy Study
Official Title:	Cognitive-Behavioural Therapy Versus Short-Term Psychodynamic Psychotherapy: a Randomised Clinical Trial

Further study details as provided by Copenhagen Trial Unit, Center for Clinical Intervention Research:

Primary Outcome Measures:

Two primary outcome measures were included 0, 6 and 12 month after treatment: the Health Anxiety Inventory (HAI), which is an 18-item, self-report questionnaire and the Hamilton Anxiety Rating Scale (HAM-A).

Secondary Outcome Measures:

Several secondary outcome measures were included 0, 6 and 12 month after treatment: Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Hamilton Rating Scale for Depression (HAM-D) and Global Assessment Functioning (GAF).

Estimated Enrollment:	80
Study Start Date:	August 2001
Estimated Study Completion Date:	March 2005

Detailed Description:

Background: The central feature of hypochondriasis is preoccupation or fear of having a serious disease based on misinterpretation of bodily signs. Psychotherapeutic treatments have developed with focus on different aspects of the condition. Several controlled trials have examined the effectiveness of different treatment strategies.

Hypothesis: Hypochondriasis is accessible for treatment. Specific cognitive treatment focused on misinterpretation of bodily sensations is more effective than short-term non-specific psychodynamic psychotherapy.

Method: Patients with hypochondriasis were randomisation to cognitive behavioural therapy (CBT), psychodynamic psychotherapy, or waiting list. Patients on waiting list were subsequently randomised to CBT or dynamic psychotherapy. The patients received six-teen sessions over a period of six month. Follow-up assessments were made six and twelve month after treatment.

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

(1) age between 18 and 65 years, (2) Danish as native language, (3) fulfilment of the ICD-10 research criteria for hypochondriasis (3), (4) health anxiety to a significant degree: a score more than 17 on the health anxiety inventory (HAI) (5).

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Exclusion Criteria:

(1) current psychotic condition, (2) current substance abuse, (3) a medical condition which demanded immediate treatment, (4) psychopharmacological treatment initiated or increased during the last 6 weeks before treatment, and (5) previous cognitive behavioural treatment.

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Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00208247

Sponsors and Collaborators

Copenhagen Trial Unit, Center for Clinical Intervention Research

Bispebjerg Hospital

Investigators

Study Director:	Morten Birket-Smith, DMSc	Liaison Psychiatric Unit, Bispebjerg Hospital, 2400 NV Copenhagen, Denmark
Principal Investigator:	Per Sorensen, MD	Liaison Psychiatric Unit, Bispebjerg Hospital, 2400-NV Copenhagen, Denmark

More Information

Study ID Numbers:	2001-11-DP-82-RKF-21
Study First Received:	September 13, 2005
Last Updated:	September 13, 2005
ClinicalTrials.gov Identifier:	NCT00208247
Health Authority:	Denmark: The Regional Committee on Biomedical Research Ethics

Study placed in the following topic categories:

Hypochondriasis
Mental Disorders
Somatoform Disorders

ClinicalTrials.gov processed this record on January 16, 2009