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Airways Dysfunction Following WTC Dust Exposure
This study is ongoing, but not recruiting participants.
Sponsored by: New York University School of Medicine
Information provided by: New York University School of Medicine
ClinicalTrials.gov Identifier: NCT00395330
  Purpose

In the weeks following the terrorist attacks of September 11, 2001, many patients presented to their physicians with complaints related to exposure to the debris. These included nose and throat complaints (drip, congestion, sore throat), increased GE reflux (heartburn, regurgitation, retrosternal chest burning) and respiratory symptoms (worsening cough, wheezing, shortness of breath, chest tightness, sleep disturbance). In addition, there was a disproportionate rate of self-reported worsening asthma symptoms in patients living in Lower New York 5-9 weeks after the attack; those with exposure to the dust cloud fared worse. The functional abnormalities of firefighters with exposures to dust at the WTC site has been recently described. However, the effects of WTC dust exposure on pulmonary function in residents and workers near the WTC site remain unclear. This study will retrospectively review the charts of all patients referred to the pulmonary function laboratory for evaluation of symptoms following exposure to WTC dust. The main objectives for this study will be to characterize the functional abnormalities in these subjects.


Condition
Pulmonary Diseases

U.S. FDA Resources
Study Type: Observational
Study Design: Natural History, Cross-Sectional, Convenience Sample, Retrospective Study
Official Title: Airways Dysfunction Following WTC Dust Exposure

Further study details as provided by New York University School of Medicine:

Estimated Enrollment: 500
Study Start Date: April 2003
Estimated Study Completion Date: October 2006
  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • age 18-80
  • referral for pulmonary function evaluation of respiratory symptoms following exposure to WTC dust

Exclusion Criteria:

  • inability to perform testing
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00395330

Sponsors and Collaborators
New York University School of Medicine
Investigators
Principal Investigator: Kenneth I Berger, MD New York University School of Medicine
  More Information

Publications indexed to this study:
Study ID Numbers: H06-714
Study First Received: November 1, 2006
Last Updated: November 1, 2006
ClinicalTrials.gov Identifier: NCT00395330  
Health Authority: United States: Institutional Review Board

Keywords provided by New York University School of Medicine:
Respiratory Function Tests
Oscillometry
World Trade Center Disaster
Environmental Exposure
Distal Airways

Study placed in the following topic categories:
Respiratory Tract Diseases
Lung Diseases

ClinicalTrials.gov processed this record on January 16, 2009