Hypercoagulability After Breast Cancer Surgery - Full Text View

Sponsored by:	Institut Bergonié
Information provided by:	Institut Bergonié
ClinicalTrials.gov Identifier:	NCT00210197

Purpose

The risk of deep venous thrombosis after radical breast surgery is known. The objective of this study is to explore hypercoagulability after radical breast cancer surgery by studying several factors for haemostasis before, during and after surgery. Ultrasound Doppler examination is realised between 24 and 72 hours post-operatively. Hypercoagulability is defined by a significant increasing level of thrombin-antithrombin, D-dimer and the endogen thrombin potential.

Condition	Intervention
Breast Cancer Blood Coagulation Disorders	Procedure: Blood collection (pre and postoperative): plasma coagulation parameters

Genetics Home Reference related topics: breast cancer factor V Leiden thrombophilia hemophilia

MedlinePlus related topics: Bleeding Disorders Breast Cancer Cancer

U.S. FDA Resources

Study Type:	Observational
Study Design:	Prospective
Official Title:	Plasma Coagulation Parameters and Hypercoagulability After Breast Cancer Surgery

Further study details as provided by Institut Bergonié:

Estimated Enrollment:	45
Study Start Date:	January 2005
Study Completion Date:	January 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion criteria:

Breast cancer
mastectomy

Exclusion criteria:

thrombophilia
anticoagulant treatment

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00210197

Locations

France
Institut Bergonié - Centre Régional de Luttre Contre le Cancer de Bordeaux et du Sud Ouest
Bordeaux, France, 33076

Sponsors and Collaborators

Institut Bergonié

Investigators

Principal Investigator:

Youssef KABBANI, MD

Institut Bergonié

More Information

Study ID Numbers:	IB2005-06, EHC
Study First Received:	September 13, 2005
Last Updated:	October 31, 2007
ClinicalTrials.gov Identifier:	NCT00210197
Health Authority:	France: Afssaps - French Health Products Safety Agency

Keywords provided by Institut Bergonié:

Hypercoagulability
Plasma coagulation parameters
Breast cancer

Study placed in the following topic categories:

Hemorrhagic Disorders
Skin Diseases
Hematologic Diseases
Thrombophilia
Blood Coagulation Disorders

Vascular Diseases
Breast Neoplasms
Hemostatic Disorders
Breast Diseases

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 16, 2009