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Sponsored by: |
National Eye Institute (NEI) |
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Information provided by: | National Institutes of Health Clinical Center (CC) |
ClinicalTrials.gov Identifier: | NCT00005761 |
This study will determine whether certain factors in the blood are associated with the severity of diabetic retinopathy.
Patients age 10 years and older with diabetes mellitus and diabetic retinopathy may be eligible for this study. Those enrolled will represent a range of diabetic retinopathy from minimal to severe. Participants will undergo the following procedures:
This study may lead to a better understanding of how diabetic retinopathy develops and progresses.
Condition |
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Diabetic Retinopathy |
Study Type: | Observational |
Official Title: | Study of Association of Serum Factors With Diabetic Retinopathy |
Estimated Enrollment: | 225 |
Study Start Date: | May 2000 |
50 patients with a range of severity of diabetic retinopathy will be evaluated once for serum levels of cell adhesion molecules, chemokines and vascular endothelial growth factor. This study may lead to a better understanding of the pathogenesis of diabetic retinopathy and the identifying of possible targets for treatment.
Patients will undergo an ocular exam and ophthalmic photography. Blood is drawn for the analysis of these serum factors.
Ages Eligible for Study: | 10 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Subjects will be able to enroll if they:
Have a clinical diagnosis of diabetes based on any one of the following criteria:
EXCLUSION CRITERIA:
Subjects will not be eligible if they:
Have any of the following ocular characteristics or conditions in both eyes:
Contact: Patient Recruitment and Public Liaison Office | (800) 411-1222 | prpl@mail.cc.nih.gov |
Contact: TTY | 1-866-411-1010 |
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | Recruiting |
Bethesda, Maryland, United States, 20892 |
Study ID Numbers: | 000135, 00-EI-0135 |
Study First Received: | May 26, 2000 |
Last Updated: | October 6, 2008 |
ClinicalTrials.gov Identifier: | NCT00005761 |
Health Authority: | United States: Federal Government |
Types 1 & 2 Diabetes Cell Adhesion Molecules Chemokines Vascular Endothelial Growth Factor |
Cross-sectional Serum Levels Diabetic Retinopathy |
Diabetic Retinopathy Eye Diseases Vascular Diseases Diabetes Mellitus Endocrine System Diseases Adhesions |
Endocrinopathy Endothelial Growth Factors Diabetes Complications Retinal Diseases Diabetic Angiopathies |
Cardiovascular Diseases |