Study of Low Bone Mass in Premenopausal or Perimenopausal Women

This study has been completed.

Sponsors and Collaborators:	National Center for Research Resources (NCRR) Columbia University
Information provided by:	National Center for Research Resources (NCRR)
ClinicalTrials.gov Identifier:	NCT00005101

Purpose

OBJECTIVES:

I. Determine the possible causes of bone loss in premenopausal or perimenopausal women.

Condition
Osteoporosis

MedlinePlus related topics: Osteoporosis

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening

Further study details as provided by National Center for Research Resources (NCRR):

Study Start Date:

February 1998

Detailed Description:

PROTOCOL OUTLINE: Patients undergo physical examination and complete history with emphasis on risk factors for osteoporosis and screening for occult secondary causes of osteoporosis through blood serum and 24 hour urine collection.

Patients with more than 6 months since prior bone mineral density measurements or who did not receive measurements at participating center, undergo dual energy x-ray absorptiometry over 30 minutes for bone mineral density measurements.

Eligibility

Ages Eligible for Study:	16 Years to 54 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

Low bone mass (T score less than -2.0) with no secondary cause on routine exam
Premenopausal

Perimenopausal

--Prior/Concurrent Therapy--

Chemotherapy: No prior or concurrent chemotherapeutic agents
Endocrine therapy: No prior or concurrent glucocorticoids or suppressive doses of thyroid hormone
Other: No prior or concurrent anticonvulsants

--Patient Characteristics--

Hematopoietic: No multiple myeloma
Other: No hyperparathyroidism No thyrotoxicosis No anorexia nervosa No Paget's disease of bone No rheumatoid arthritis No Cushing's syndrome No malabsorption syndrome No type I diabetes mellitus

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00005101

Locations

United States, New York
Columbia University College of Physicians and Surgeons
New York, New York, United States, 10032

Sponsors and Collaborators

National Center for Research Resources (NCRR)

Columbia University

Investigators

Study Chair:

Elizabeth Shane

Columbia University

More Information

Study ID Numbers:	NCRR-M01RR00645-2738, CPMC-IRB-8414, CPMC-GCRC-2738
Study First Received:	April 6, 2000
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00005101
Health Authority:	United States: Federal Government

Keywords provided by National Center for Research Resources (NCRR):

disease-related problem/condition
osteoporosis
rare disease

Study placed in the following topic categories:

Musculoskeletal Diseases
Rare Diseases
Osteoporosis
Bone Diseases, Metabolic
Bone Diseases

ClinicalTrials.gov processed this record on January 16, 2009