Rate of Postpyloric Migration of Spiral Nasojejunal Tubes in Brain Injured Patients - Full Text View

Sponsored by:	Capital Medical University
Information provided by:	Capital Medical University
ClinicalTrials.gov Identifier:	NCT00562146

Purpose

The success rate of unguided nasojejunal feeding tube insertion will be determined in acute brain injured patients. Factors influencing tube self-progression will be evaluated.

Condition	Intervention
Acute Brain Injury	Procedure: placement of spiral nasojejunal tube

MedlinePlus related topics: Traumatic Brain Injury

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Prospective
Official Title:	Rate of Postpyloric Migration of Spiral Nasojejunal Tubes in Brain Injured Patients

Further study details as provided by Capital Medical University:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	120
Study Start Date:	December 2007
Study Completion Date:	September 2008
Primary Completion Date:	September 2008 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
1 Successful progression of spiral tube to duodenum within 3 days	Procedure: placement of spiral nasojejunal tube spiral nasojejunal tube will be placed after enrollment of the patients
2 Failure of progression to duodenum within 3 days	Procedure: placement of spiral nasojejunal tube spiral nasojejunal tube will be placed after enrollment of the patients

Detailed Description:

Nutrition support is important in brain injured patients. Several studies have shown that small bowel feeding compared with gastric feeding may be associated with a reduction in pneumonia in critically ill patients. The Canadian Clinical Practice Guidelines recommended that small bowel feedings should be considered for patients at high risk for intolerance to enteral nutrition.

There are several methods to place postpyloric tube, but there is a high success rate with endoscopic or radiological assistance. However, they are time consuming procedures, which is of limited availability at bedside and requires trained staff.

Nasojejunal tube with spiral end (Flocare Bengmark NJ tube) has been used for bedside placement for 10 years. But only limited data are available for success rate, especially in brain injured patients. The aim of this study is to access the success rate and influencing factors of spiral end nasojejunal tube in such a population.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Acute brain injured patients admitted to Neuro-ICU will be consecutively enrolled.

Criteria

Inclusion Criteria:

Acute brain injured patients admitted to Neuro-ICU

Exclusion Criteria:

Patients' stay in ICU shorter than 3 days
Patients with contraindication to naso-feeding tube placement

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00562146

Locations

China
ICU, Beijing Tiantan Hospital, Capital Medical University
Beijing, China, 100050

Sponsors and Collaborators

Capital Medical University

Investigators

Study Chair:

Jian-Xin Zhou, MD

ICU, Beijing Tiantan Hospital, Capital Medical University

More Information

Responsible Party:	ICU, Beijing Tiantan Hospital, Capital Medical University ( Jian-Xin Zhou )
Study ID Numbers:	BJTTH-ICU-07-011, BJTTH-ICU-07-011
Study First Received:	November 20, 2007
Last Updated:	October 27, 2008
ClinicalTrials.gov Identifier:	NCT00562146
Health Authority:	China: Ministry of Health

Keywords provided by Capital Medical University:

nutrition
enteral access

Study placed in the following topic categories:

Craniocerebral Trauma
Wounds and Injuries
Disorders of Environmental Origin
Central Nervous System Diseases

Trauma, Nervous System
Brain Diseases
Brain Injuries

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on January 14, 2009