![]() |
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
Sponsors and Collaborators: |
Barwon Health University of Melbourne National Health and Medical Research Council, Australia |
---|---|
Information provided by: | Barwon Health |
ClinicalTrials.gov Identifier: | NCT00430547 |
The purpose of this study is to determine whether radioactive iodine, as compared to anti-thyroid medications, is a risk factor for the development or progression of thyroid-associated ophthalmopathy in patients with hyperthyroidism due to Graves' disease. The other aim of this study is to determine the incidence of the various ophthalmopathy subtypes and the utility of orbital antibodies in the diagnosis, classification and monitoring of patients with thyroid-associated ophthalmopathy.
Condition | Intervention |
---|---|
Graves' Ophthalmopathy |
Drug: Carbimazole, radio-active iodine (I131) |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study |
Official Title: | Thyroid-Associated Ophthalmopathy Subtypes and Orbital Antibodies |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Australia, Victoria | |
Barwon Health - The Geelong Hospital | |
Geelong, Victoria, Australia, 3220 |
Principal Investigator: | Jack R Wall, BMBS, FRACP, PhD | The University of Sydney |
Study ID Numbers: | 03/53 |
Study First Received: | February 1, 2007 |
Last Updated: | February 1, 2007 |
ClinicalTrials.gov Identifier: | NCT00430547 |
Health Authority: | Australia: National Health and Medical Research Council |
Goiter Autoimmune Diseases Graves Ophthalmopathy Eye Diseases Graves Disease Endocrine System Diseases Graves' disease Antibodies |
Eye Diseases, Hereditary Iodine Carbimazole Orbital Diseases Endocrinopathy Thyroid Diseases Hyperthyroidism Immunoglobulins |
Antithyroid Agents Immune System Diseases Hormone Antagonists Physiological Effects of Drugs |
Hormones, Hormone Substitutes, and Hormone Antagonists Pharmacologic Actions Exophthalmos |