Havlin RH, Blanco FJ, Tycko R Constraints on Protein Structure in HIV-1 Rev and Rev-RNA Supramolecular Assemblies from Two-Dimensional Solid State Nuclear Magnetic Resonance. Biochemistry , 2007. [Full Text/Abstract]
Bu Z, Shi Y, Callaway DJ, Tycko R Molecular alignment within beta-sheets in Abeta(14-23) fibrils: solid-state NMR experiments and theoretical predictions. Biophys J (92): 594-602, 2007. [Full Text/Abstract]
Tycko R Symmetry-based constant-time homonuclear dipolar recoupling in solid state NMR. J Chem Phys (126): 064506, 2007. [Full Text/Abstract]
Shewmaker F, Wickner RB, Tycko R Amyloid of the prion domain of Sup35p has an in-register parallel beta-sheet structure. Proc Natl Acad Sci U S A (103): 19754-9, 2006. [Full Text/Abstract]
Tycko R Characterization of amyloid structures at the molecular level by solid state nuclear magnetic resonance spectroscopy. Methods Enzymol (413): 103-22, 2006. [Full Text/Abstract]
Lazar KL, Kurutz JW, Tycko R, Meredith SC Encapsulation and NMR on an aggregating peptide before fibrillogenesis. J Am Chem Soc (128): 16460-1, 2006. [Full Text/Abstract]
Petkova AT, Yau WM, Tycko R Experimental Constraints on Quaternary Structure in Alzheimer's beta-Amyloid Fibrils. Biochemistry(45): 498-512, 2006. [Full Text/Abstract]
Paravastu AK, Tycko R Frequency-selective homonuclear dipolar recoupling in solid state NMR. J Chem Phys (124): 194303, 2006. [Full Text/Abstract]
Tycko R Molecular structure of amyloid fibrils: insights from solid-state NMR. Q Rev Biophys (39): 1-55, 2006. [Full Text/Abstract]
Paravastu AK, Petkova AT, Tycko R Polymorphic fibril formation by residues 10-40 of the Alzheimer''s beta-amyloid peptide. Biophys J (90): 4618-29, 2006. [Full Text/Abstract]
Tycko R Solid-state NMR as a probe of amyloid structure. Protein Pept Lett (13): 229-34, 2006. [Full Text/Abstract]
Sharpe S, Yau WM, Tycko R Structure and Dynamics of the HIV-1 Vpu Transmembrane Domain Revealed by Solid-State NMR with Magic-Angle Spinning. Biochemistry (45): 918-33, 2006. [Full Text/Abstract]
Sciarretta KL, Gordon DJ, Petkova AT, Tycko R, Meredith SC Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry (44): 6003-14, 2005. [Full Text/Abstract]
Sharpe S, Yau WM, Tycko R Expression and purification of a recombinant peptide from the Alzheimer's beta-amyloid protein for solid-state NMR. Protein Expr Purif(42): 200-10, 2005. [Full Text/Abstract]
Buchete NV, Tycko R, Hummer G Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments. J Mol Biol(353): 804-21, 2005. [Full Text/Abstract]
Chan JC, Oyler NA, Yau WM, Tycko R Parallel beta-sheets and polar zippers in amyloid fibrils formed by residues 10-39 of the yeast prion protein Ure2p. Biochemistry (44): 10669-80, 2005. [Full Text/Abstract]
Havlin RH, Tycko R Probing site-specific conformational distributions in protein folding with solid-state NMR. Proc Natl Acad Sci U S A (102): 3284-9, 2005. [Full Text/Abstract]
Petkova AT, Leapman RD, Guo Z, Yau WM, Mattson MP, Tycko R Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils. Science(307): 262-5, 2005. [Full Text/Abstract]
Oyler NA, Tycko R Absolute structural constraints on amyloid fibrils from solid-state NMR spectroscopy of partially oriented samples. J Am Chem Soc (126): 4478-9, 2004. [Full Text/Abstract]
Chan JC, Tycko R Broadband rotational resonance in solid state NMR spectroscopy. J Chem Phys (120): 8349-52, 2004. [Full Text/Abstract]
Gordon DJ Balbach JJ Tycko R Meredith SC Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel. Biophys J (86): 428-34, 2004. [Full Text/Abstract]
De Dios AC, Sears DN, Tycko R NMR studies of peptide T, an inhibitor of HIV infectivity, in an aqueous environment. J Pept Sci (10): 622-30, 2004. [Full Text/Abstract]
Tycko R Progress towards a molecular-level structural understanding of amyloid fibrils. Curr Opin Struct Biol (14): 96-103, 2004. [Full Text/Abstract]
Tycko R Sensitivity enhancement in two-dimensional solid-state NMR spectroscopy by transverse mixing. Chemphyschem (5): 863-8, 2004. [Full Text/Abstract]
Petkova AT Buntkowsky G Dyda F Leapman RD Yau WM Tycko R Solid state NMR reveals a pH-dependent antiparallel beta-sheet registry in fibrils formed by a beta-amyloid peptide. J Mol Biol (335): 247-60, 2004. [Full Text/Abstract]
Sharpe S, Kessler N, Anglister JA, Yau WM, Tycko R Solid-state NMR yields structural constraints on the V3 loop from HIV-1 Gp120 bound to the 447-52D antibody Fv fragment. J Am Chem Soc (126): 4979-90, 2004. [Full Text/Abstract]
Tycko R Ishii Y Constraints on supramolecular structure in amyloid fibrils from two-dimensional solid-state NMR spectroscopy with uniform isotopic labeling. J Am Chem Soc (125): 6606-7, 2003. [Full Text/Abstract]
Tycko R Insights into the amyloid folding problem from solid-state NMR. Biochemistry (42): 3151-9, 2003. [Full Text/Abstract]
Antzutkin ON Balbach JJ Tycko R Site-specific identification of non-beta-strand conformations in Alzheimer''s beta-amyloid fibrils by solid-state NMR. Biophys J (84): 3326-35, 2003. [Full Text/Abstract]
Chan JC Tycko R Solid-state NMR spectroscopy method for determination of the backbone torsion angle psi in peptides with isolated uniformly labeled residues. J Am Chem Soc (125): 11828-9, 2003. [Full Text/Abstract]
Petkova AT Ishii Y Balbach JJ Antzutkin ON Leapman RD Delaglio F Tycko R A structural model for Alzheimer''s beta -amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci U S A (99): 16742-7, 2002. [Full Text/Abstract]
Petkova AT Tycko R Sensitivity enhancement in structural measurements by solid state NMR through pulsed spin locking. J Magn Reson (155): 293-9, 2002. [Full Text/Abstract]
Antzutkin ON Leapman RD Balbach JJ Tycko R Supramolecular structural constraints on Alzheimer''s beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance. Biochemistry (41): 15436-50, 2002. [Full Text/Abstract]
Balbach JJ Petkova AT Oyler NA Antzutkin ON Gordon DJ Meredith SC Tycko R Supramolecular structure in full-length Alzheimer''s beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance. Biophys J (83): 1205-16, 2002. [Full Text/Abstract]
Tycko R Biomolecular solid state NMR: advances in structural methodology and applications to peptide and protein fibrils. Annu Rev Phys Chem (52): 575-606, 2001. [Full Text/Abstract]
Ishii Y Markus MA Tycko R Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel. J Biomol NMR (21): 141-51, 2001. [Full Text/Abstract]
Ishii Y Yesinowski JP Tycko R Sensitivity enhancement in solid-state (13)C NMR of synthetic polymers and biopolymers by (1)H NMR detection with high-speed magic angle spinning. J Am Chem Soc (123): 2921-2, 2001. [Full Text/Abstract]
Blanco FJ Hess S Pannell LK Rizzo NW Tycko R Solid-state NMR data support a helix-loop-helix structural model for the N-terminal half of HIV-1 Rev in fibrillar form. J Mol Biol (313): 845-59, 2001. [Full Text/Abstract]
Tycko R Solid-state nuclear magnetic resonance techniques for structural studies of amyloid fibrils. Methods Enzymol (339): 390-413, 2001. [Full Text/Abstract]
Tycko R, Blanco FJ, Ishii Y. Alignment of biopolymers in strained gels: a new way to create detectable dipole-dipole couplings in high resolution biomolecular NMR. Journal of the American Chemical Society , 2000.
Balbach JJ Ishii Y Antzutkin ON Leapman RD Rizzo NW Dyda F Reed J Tycko R Amyloid fibril formation by A beta 16-22, a seven-residue fragment of the Alzheimer''s beta-amyloid peptide, and structural characterization by solid state NMR. Biochemistry (39): 13748-59, 2000. [Full Text/Abstract]
Antzutkin ON Balbach JJ Leapman RD Rizzo NW Reed J Tycko R Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer''s beta-amyloid fibrils. Proc Natl Acad Sci U S A (97): 13045-50, 2000. [Full Text/Abstract]
Balbach JJ Yang J Weliky DP Steinbach PJ Tugarinov V Anglister J Tycko R Probing hydrogen bonds in the antibody-bound HIV-1 gp120 V3 loop by solid state NMR REDOR measurements. J Biomol NMR (16): 313-27, 2000. [Full Text/Abstract]
Ishii Y Tycko R Sensitivity enhancement in solid state (15)N NMR by indirect detection with high-speed magic angle spinning. J Magn Reson (142): 199-204, 2000. [Full Text/Abstract]
Tycko R Solid-state NMR as a probe of amyloid fibril structure. Curr Opin Chem Biol (4): 500-6, 2000. [Full Text/Abstract]
Tycko R Berger AE Dual processing of two-dimensional exchange data in magic angle spinning NMR of solids. J Magn Reson (141): 141-7, 1999. [Full Text/Abstract]
Tycko R Selection rules for multiple quantum NMR excitation in solids: derivation from time-reversal symmetry and comparison with simulations and (13)C NMR experiments. J Magn Reson (139): 302-7, 1999. [Full Text/Abstract]
Weliky DP Bennett AE Zvi A Anglister J Steinbach PJ Tycko R Solid-state NMR evidence for an antibody-dependent conformation of the V3 loop of HIV-1 gp120. Nat Struct Biol (6): 141-5, 1999. [Full Text/Abstract]
Michal CA, Tycko R. Nuclear spin polarization transfer with a single radio-frequency field in optically pumped indium phosphide. Physical Review Letters(81): 3988, 1998.
Tycko R Optical pumping in indium phosphide: 31P NMR measurements and potential for signal enhancement in biological solid state NMR. Solid State Nucl Magn Reson (11): 1-9, 1998. [Full Text/Abstract]