Compounds In Testing
Each material is given in the diet at the following levels (part per million (PPM) by weight).
Cohort 1:
Compound |
Concentration in food |
Age at treatment initiation |
Aspirin |
20 ppm |
4 months |
NFP |
200 ppm |
4 months |
NDGA |
2,500 ppm |
9 months |
4-OH-PBN |
315 ppm |
4 months |
Cohort 2:
Compound |
Concentration in food |
Age at treatment initiation |
CAPE |
30 ppm |
4 months |
CAPE |
300 ppm |
4 months |
Enalapril Maleate |
120 ppm |
4 months< |
Rapamycin |
14 ppm |
20 month |
Cohort 3:
Compound |
Concentration in food |
Age at treatment initiation |
Rapamycin |
14 ppm |
9 months |
Simvastatin |
12 ppm |
10 months |
Simvastatin |
120 ppm |
10 months |
Resveratrol |
300 ppm |
12 months |
Resveratrol |
1200 ppm |
12 months |
Cohort 4:
Compound |
Concentration in food |
Age at treatment initiation |
Resveratrol |
300 ppm |
4 months |
N-acetyl-cysteine |
5000 ppm |
10 months |
Oxaloacetic acid |
2200 ppm |
4 months |
Green tea extract |
2000 ppm |
4 months |
Curcumin |
2000 ppm |
4 months |
Medium Chain Triglyceride Oil |
60000 ppm |
4 months |
Page last updated Sep 26, 2008