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Plague is transmitted to humans by fleas or by direct exposure to infected tissues or respiratory droplets; the disease is characterized by fever, chills, headache, malaise, prostration, and leukocytosis that manifests in one or more of the following principal clinical forms:
Presumptive
Confirmatory
Suspected: a clinically compatible case without presumptive or confirmatory laboratory results
Probable: a clinically compatible case with presumptive laboratory results
Confirmed: a clinically compatible case with confirmatory laboratory results
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