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Agricultural Research Service United States Department of Agriculture
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Darrell R Kapczynski
Exotic and Emerging Avian Viral Diseases Research Unit
Microbiologist

Phone: (706) 546-3471
Fax: (706) 546-3161
USDA, ARS, SAA
SPRL
934 COLLEGE STATION ROAD
ATHENS, GA, 30605

Projects
GENOMIC AND FUNCTIONAL ANALYSIS OF THE MUCOSAL IMMUNE RESPONSE AND ITS ROLE IN PROTECTION AGAINST RESPIRATORY PATHOGENS IN POULTRY
Appropriated (D)
  Accession Number: 411029
EVALUATION OF RECOMBINANT HERPRESVIRUS-OF-TURKEYS VACCINE AGAINST AVIAN INFLUENZA H5N1
Trust (T)
  Accession Number: 415068

Publications
In vitro comparison of the cytokine response to avian influenza virus from peripheral blood lymphocyles isolated from chickens differing in Mx631 gene polymorphism - (Abstract) - (14-Feb-09)
Differences in sialic acid repertoire provides a molecular platform for replication of both avian and mammalian influenza viruses in turkeys but not chickens - (Abstract) - (28-Jan-09)
Cross reactive antibody and cytotoxic T lymphocytes from avian influenza H9N2 infected chickens against homologous and heterologous avian influenza isolates - (Abstract) - (28-Jan-09)
Role of host gene expression on infection, disease and lethality of HPAI virus infection in ducks - (Abstract) - (28-Jan-09)
Vaccine induced protection from egg production losses in commercial turkey breeder hens following experimental challenge with a triple reassortant H3N2 avian influenza virus - (Peer Reviewed Journal) - (11-Sep-08)
Influenza vaccines for avian species - (Book/Chapter) - (29-Jul-08)
The influence of immunogenomics on the innate immune response to avian influenza-comparison of toll-like receptor 7 and cytokine responses between chickens and ducks - (Abstract)
Kapczynski, D.R., Smith, A.L., Philbin, V., Liljebjelke, K.A., Pantin Jackwood, M.J. 2008. The influence of immunogenomics on the innate immune response to avian influenza-comparison of toll-like receptor 7 and cytokine responses between chickens and ducks [abstract]. In: Proceedings of the American Association of Avian Pathologists annual meeting, July 19-23, 2008, New Orleans, Louisiana. p. 85.
The role of vaccines and biosecurity in control of H3N2 swine influenza infection in turkey breeder flocks - (Proceedings/Symposium)
Tilley, B., Kapczynski, D.R., Gonder, E., Smith, C., Jackson, S. 2008. The role of vaccines and biosecurity in control of H3N2 swine influenza infection in turkey breeder flocks. In: Proceedings of the American Association of Avian Pathologists Annual Meeting, July 19-23, 2008, New Orleans, Lousiana. CDROM.
Strategies and challenges for eliciting immunity against avian influenza virus in birds - (Peer Reviewed Journal)
Swayne, D.E., Kapczynski, D.R. 2008. Strategies and challenges for eliciting immunity against avian influenza virus in birds. Immunological Reviews. 225:314-331.
Development and evaluation of a potential universal Salmonella-vectored avian influenza vaccine - (Abstract)
Hargis, B.M., Layton, S.L., Kapczynski, D.R., Cole, K., Cox, M.M., Ywon, Y.M., Bergham, L.R., Liljebjelke, K.A., Bottje, W.J. 2008. Development and evaluation of a potential universal Salmonella-vectored avian influenza vaccine [abstract]. Poultry Science Association Centennial Meeting, July 20-23, 2008, Ontario, Canada. CDROM.
Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys. - (Abstract)
Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Pathogenic assessment of recombinant avian metapneumovirus subgroup C viruses in SPF chickens and turkeys [abstract]. In: Abstracts of the 14th International Congress of Virology, Istanbul, Turkey. p. 318.
Transcriptional analysis of the innate immune response using the avian innate immunity microarray - (Abstract)
Chung, I.T., Keeler, C.L., Kapczynski, D.R., Doughtery, L., Maughan, M.N. 2008. Transcriptional analysis of the innate immune response using the avian innate immunity microarray [abstract]. Immunobiology and Pathogenesis of Influenza Infection meeting, June 1-3, 2008, Atlanta, Georgia. CDROM.
Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development - (Abstract)
Yu, Q., Estevez, C. N., King, D. J., Kapczynski, D. R., Zsak, L. 2008. Generation of recombinant avian metapneumovirus subgroup C viruses for pathogenesis studies and vaccine development [abstract]. In: Proceedings of the 27th Annual Meeting of American Society for Virology, Cornell, New York. p. 296.
ACUTE PHASE IMMUNE GENE PROFILING OF SPLEEN AND PEYER¿S PATCH IN NAÏVE AND VACCINATED CHICKENS FOLLOWING AVIAN INFLUENZA A (H5N1) VIRUS INFECTION - (Abstract)
Kim, C., Lillehoj, H.S., Hong, Y.H., Kim, D., Kapczynski, D.R., Keeler, C.L. 2008. Acute phase immune gene profiling of spleen and peyer¿s patch in naïve and vaccinated chickens following avian influenza a (h5n1) virus infection. 11th Annual Conf. on Vaccine Research, Baltimore, MD.
Microarray analysis following infection with highly pathogenic avian influenza H5N1 virus in naive and vaccinated SPF chickens - (Abstract)
Kapczynski, D.R., Afonso, C.L., Pantin Jackwood, M.J., Liljebjelke, K.A., Sarmento, L., Suarez, D.L., Swayne, D.E. 2008. Microarray analysis following infection with highly pathogenic avian influenza H5N1 virus in naive and vaccinated SPF chickens [abstract]. In: Proceedings of Avian Immunology Research Group Conference, June 24-27, 2008, Queensland, Australia. p. 22.
Polymorphism in chicken Mx gene influences susceptibility to avian influenza virus infection - (Abstract)
Ewald, S.J., Livant, E.J., Kaltenboeck, L., Kapczynski, D.R., Suarez, D.L., Ralph, J., Mcleod, S., Miller, C. 2008. Polymorphism in chicken Mx gene influences susceptibility to avian influenza virus infection [abstract]. Avian Immunology Research Group. p. 1.
Determination of minimum units of hemagglutinin content of emulsified inactivated Newcastle disease virus vaccine for clinical protection of white leghorn chickens from lethal challenge - (Peer Reviewed Journal)
Liljebjelke, K.A., King, D.J., Kapczynski, D.R. 2008. Determination of minimum hemagglutinin units in an inactivated Newcastle disease virus vaccine for clinical protection of chickens from exotic Newcastle disease virus challenge. Avian Diseases. 52:260-268.
Gene expression responses to highly pathogenic avian influenza H5N1 virus infections in ducks - (Abstract)
Pantin Jackwood, M.J., Kapczynski, D.R., Wasilenko, J.L., Sarmento, L., Afonso, C.L. 2008. Gene expression responses to highly pathogenic avian influenza H5N1 virus infections in ducks [abstract]. 145th American Medical Association Annual Meeting, July 20-23, 2008, New Orleans, Louisiana. 2008 CDROM.
Immediate early responses of avian tracheal epithelial cells to infection with highly pathogenic avian invluenza virus - (Peer Reviewed Journal)
Sarmento, L., Pantin Jackwood, M.J., Kapczynski, D.R., Swayne, D.E., Afonso, C.L. 2008. Immediate early responses of avian tracheal epithelial cells to infection with highly pathogenic avian invluenza virus. Biologicals. 132:175-183.
Construction of a fowl adenovirus recombinant to express avian metapneumovirus glycoprotein - (Abstract) - (19-Dec-07)
Comparison of inactivated H3 avian influenza vaccines to protect turkey hens against egg production losses following challenge with a recent H3N2 field isolate - (Abstract)
Kapczynski, D.R., Liljebjelke, K.A., Gonder, E., Lippert, R., Tilley, B. 2008. Comparison of inactivated H3 avian influenza vaccines to protect turkey hens against egg production losses following challenge with a recent H3N2 field isolate [abstract]. In: Proceedings of the 23rd World Poultry Congress, June 29-July 4, 2008, Brisbane, Australia. CDROM.
Research update on exotic and emerging poultry diseases - (Proceedings/Symposium)
Pantin Jackwood, M.J., Suarez, D.L., Zsak, L., Spackman, E., Kapczynski, D.R., King, D.J., Afonso, C.L., Day, J.M., Spatz, S.J., Yu, Q., Swayne, D.E. 2007. Research update on exotic and emerging poultry diseases. In: Proceedings of the 111th Annual Meeting of the U. S. Animal Health Association, Reno, Nevada, October 22-23, 2007. p. 702-707. Available: http://www.usaha.org/meetings/2007/2007_USAHA_Proceedings.pdf.
Mucosal vaccination with formalin-inactivated avian metapneumovirus Subtype C reduces clinical signs of disease but enhances local pathology of turkeys following challenge - (Peer Reviewed Journal)
Kapczynski, D.R., Perkins, L.L., Sellers, H.S. 2008. Mucosal vaccination with formalin-inactivated avian metapneumovirus Subtype C reduces clinical signs of disease but enhances local pathology of turkeys following challenge. Avian Diseases. 52:28-33.
Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies - (Proceedings/Symposium)
Yu, Q., Estevez, C., King, D.J., Kapczynski, D.R., Zsak, L. 2007. Rescue of recombinant avian metapneumovirus subgroup C viruses from cloned DNAs for vaccine development and pathogenesis studies. In: Proceedings of 2007 Turkey Research Review and Avian Pneumovirus Symposium, September 26-27, 2007 Willmar, Minnesota. 2007 CDROM.
Studies on H5N1 avian influenza virus gene reassortants in vivo - (Abstract)
Wasilenko, J.L., Pantin Jackwood, M.J., Lee, C., Kapczynski, D.R., Sarmento, L., Spackman, E., Suarez, D.L. 2007. Studies on H5N1 avian influenza virus gene reassortants in vivo. In: Proceedings of the 4th Orthomyxoviruses Research Conference, September 21-24, 2007, MBL, Woods Hole, MA. p.73.
Pathogenesis of H5N1 avian influenza virus reassortants in chickens - (Proceedings/Symposium)
Pantin-Jackwood, M., Lee, C-W, Kapczynski, D.R., Sarmento, S., Wasilenko, J.L., Spackman, E., Suarez, D.L. 2008. Pathogenicity of H5N1 avian influenza virus reassortants in chickens. In proceedings of Options for the Control of Influenza VI, June 17-23, 2007. Toronto, ON. Canada. p. 546-548.
Vaccines, vaccination and immunology for avian influenza viruses in poultry - (Book/Chapter)
Swayne, D.E., Kapczynski, D.R. 2008. Vaccines, vaccination and immunology for avian influenza viruses in poultry. In: Swayne, D.E. editor. Avian Influenza. Ames, Iowa: Blackwell Publishing. p. 407-451.
Comparison of the pathogenicity of different H5N1 HPAI viruses in chickens and ducks - (Proceedings/Symposium)
Pantin Jackwood, M.J., Kapczynski, D.R., Wasilenko, J.L., Sarmento, L. 2007. Comparison of the pathogenicity of different H5N1 HPAI viruses in chickens and ducks. In: Proceedings of theAmerican Association of Veterinary Laboratory Diagnosticians 50th Annual Conference, October 18-24, 2007, Reno, Nevada. p.125.
Early responses of chicken lungs and spleens to infection with highly pathogenic avian influenza virus using microarray analysis - (Abstract)
Afonso, C.L., Kapczynski, D.R., Pantin Jackwood, M.J., Sarmento, L., Swayne, D.E. 2007. Early responses of chicken lungs and spleens to infection with highly pathogenic avian influenza virus using microarray analysis [abstract]. In: Proceedings of the International Symposium on Animal Genomics for Animal Health, October 23-25, 2007, Paris France. p. 59.
Immediate early responses of avian tracheal epithelial cells to infection with highly pathogenic avian influenza - (Abstract)
Afonso, C.L., Sarmento, L., Pantin Jackwood, M.J., Kapczynski, D.R., Swayne, D.E. 2007. Immediate early responses of avian tracheal epithelial cells to infection with highly pathogenic avian influenza [abstract]. In: Proceedings of the International Symposium on Animal Genomics for Animal Health, October 23-25, 2007, Paris, France. p. 16.
Pathogenesis of H5N1 avian influenza virus gene reassortants in chickens - (Abstract)
Pantin Jackwood, M.J., Lee, C.W., Kapczynski, D.R., Sarmento, L., Wasilenko, J.L., Spackman, E., Suarez, D.L. 2007. Pathogenesis of H5N1 avian influenza virus gene reassortants in chickens [abstract]. Options for the Control of Influenza VI Conference, Abstract book. June 17-23, 2007, Toronto, Canada. p. 260.
Innate immune responses to avian influenza differ between chickens and ducks - (Abstract)
Kapczynski, D.R., Pantin Jackwood, M.J. 2007. Innate immune responses to avian influenza differ between chickens and ducks [abstract]. 15th World Veterinary Poultry Congress, September 13-16, 2007, Beijing, China. p. 135.
Comparison of in vivo innate immune responses in lung and spleen tissue following infection with Asian H5N1 avian influenza viruses in ducks and chickens - (Abstract)
Kapczynski, D.R., Pantin Jackwood, M.J. 2007. Comparison of in vivo innate immune responses in lung and spleen tissue following infection with Asian H5N1 avian influenza viruses in ducks and chickens [abstract]. In: Proceedings of the 2007 American Association of Avian Pathologist Scientific Program, July 14-18, 2007, Washington, DC. p. 77.
Newcastle disease virus vaccine potency determination - (Abstract)
Liljebjelke, K.A., King, D.J., Kapczynski, D.R. 2007. Newcastle disease virus vaccine potency determination [abstract]. In: Proceedings of 2007 American Association of Avian Pathologist Scientific Program, July 14-18, 2007, Washington, DC. p. 46.
Avian influenza research update - (Proceedings/Symposium)
Suarez, D.L., Swayne, D.E., Kapczynski, D.R., Spackman, E., Pantin Jackwood, M.J. 2007. Avian influenza research update. In: Proceedings of the 110th Annual Meeting of the U.S. Animal Health Association, October 12-18, 2006, Minneapolis, Minnesota. p. 642-644.
Measurement of avian cytokines with real time RT-PCR following infection with avian influenza - (Book/Chapter)
Kapczynski, D.R., Kogut, M.H. 2008. Measurement of avian cytokines with real time RT-PCR following infection with avian influenza. In: Spackman, E., editor. Avian Influenza Virus. Totowa, NJ: Humana Press, Inc. p. 122-129.
Differential innate cytokine responses correlate with pathogenicity in chickens and ducks following infection with Asian H5N1 viruses - (Abstract)
Kapczynski, D.R., Pantin Jackwood, M.J. 2007. Differential innate cytokine responses correlate with pathogenicity in chickens and ducks following infection with Asian H5N1 viruses [abstract]. In: Proceedings of the 56th Western Poultry Disease Conference, March 26-29, 2007, Las Vegas, Nevada. p. 60.
Evaluating the cell mediated immune response of avian species to avian influenza viruses - (Book/Chapter)
Kapczynski, D.R. 2008. Evaluating the cell mediated immune response of avian species to avian influenza viruses. In: Spackman, E., editor. Avian Influenza Virus. Totowa, NJ: Humana press, Inc. p. 108-121.
Why are avian influenza viruses emerging and what tools are needed to prevent and control the infection and disease? - (Abstract)
Swayne, D.E., Suarez, D.L., Pantin Jackwood, M.J., Spackman, E., Kapczynski, D.R., Afonso, C.L. 2007. Why are avian influenza viruses emerging and what tools are needed to prevent and control the infection and disease?. In: Proceedings of the 110th Annual Meeting of the U.S. Animal Health Association, October 12-18, 2006, Minneapolis, Minnesota. p. 728-729.
Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C - (Abstract)
Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Characterization of monoclonal antibodies produced against Avian metapneumovirus Sybtype C. In: Proceedings of the 2006 Turkey Research Review and Avian Pneumovirus Symposium, September 27, 2006, Wilmar, Minnesota. 2006 CDROM.
IN VITRO AND IN VIVO DIFFERENTIAL CYTOKINE EXPRESSION BETWEEN CHICKENS AND DUCKS FOLLOWING INFECTION WITH AVIAN INFLUENZA - (Abstract)
Kapczynski, D.R., Pantin Jackwood, M.J. 2006. In vitro and in vivo differential cytokine expression between chickens and ducks following infection with avian influenza [abstract]. In: Proceedings of the 9th Avian Immunology Research Group, October 21-24, 2006, Paris, France. p. 43.
EXPERIMENTAL PATHOGENESIS FOR CHICKENS, TURKEYS, AND PIGEONS OF EXOTIC NEWCASTLE DISEASE VIRUS FROM AN OUTBREAK IN CALIFORNIA DURING 2002-2003 - (Peer Reviewed Journal)
Wakamatsu, N., King, D.J., Kapczynski, D.R., Seal, B.S., Brown, C. 2006. Experimental pathogenesis for chickens, turkeys, and pigeons of exotic Newcastle disease virus from an outbreak in California during 2002-2003. Veterinary Pathology. 43(6):925-933.
PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES PRODUCED AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C WHICH REACT TO THE NUCLEOCAPSID PROTEIN - (Peer Reviewed Journal)
Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies produced against avian metapneumovirus subtype C which react to the nucleocapsid protein. Avian Diseases. 50(3):419-424.
FULL-LENGTH SEQUENCE ANALYSIS OF FOUR IBDV STRAINS WITH DIFFERENT PATHOGENICITIES - (Peer Reviewed Journal)
Petkov, D., Linnemann, E., Kapczynski, D.R., Sellers, H. 2007. Full-length sequence analysis of four IBDV strains with different pathogenicities. Virus Genes. 34(3):315-326.
SUSCEPTIBILITY AND PROTECTION OF NAIVE AND VACCINATED RACING PIGEONS (COLUMBA LIVA) AGAINST EXOTIC NEWCASTLE DISEASE VIRUS FROM THE CALIFORNIA 2002-03 OUTBREAK - (Peer Reviewed Journal)
Kapczynski, D.R., Wise, M., King, D.J. 2006. Susceptibility and protection of naive and vaccinated racing pigeons (Columba liva) against exotic Newcastle disease virus from the California 2002-03 outbreak. Avian Diseases. 50(3):336-341.
HIGHLY VIRULENT EXOTIC NEWCASTLE DISEASE VIRUS STIMULATES DIFFERENTIAL CYTOKINE GENE EXPRESSION IN CHICKEN SPLENOCYTES FROM LOW VIRULENT LASOTA STRAIN - (Proceedings/Symposium)
Kapczynski, D.R., Holt, P.S. 2006. Highly virulent exotic Newcastle disease virus stimulates differential cytokine gene expression in chicken splenocytes from low virulent lasota strain. Proceedings of the 55th Western Poultry Disease Conference. p. 91.
DURATION OF IMMUNITY TO THE 2002-03 CALIFORNIA VIRULENT NEWCASTLE DISEASE VIRUS (VNDV) FOLLOWING A SINGLE NEWCASTLE DISEASE VACCINATION OF SPF CHICKENS - (Abstract)
Kapczynski, D.R., King, D.J. 2006. Duration of immunity to the 2002-03 california virulent Newcastle disease virus (VNDV) following a single newcastle disease vaccination of SPF chickens [abstract]. American Association of Avian Pathologists. p. 80.
PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES PRODUCED AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C WHICH REACT AGAINST THE NUCLEOCAPSID PROTEIN - (Abstract)
Yu, Q., Estevez, C., Kapczynski, D.R. 2006. Production and characterization of monoclonal antibodies produced against Avian Metapneumovirus Subtype C which react against the nucleocapsid protein [abstract]. In: Proceedings of the 2006 Annual Meeting of American Association of Avian Pathologists, July 16-19, 2006, Honolulu, HI. p. 164.
ROLE OF VERTICAL TRANSMISSION WITH AVIAN METAPNEUMOVIRUS SUBTYPE C FOLLOWING EXPERIMENTAL INFECTION OF SPF LAYING TURKEYS - (Proceedings/Symposium)
Kapczynski, D.R., Swayne, D.E. 2005. Role of vertical transmission with avian metapneumovirus subtype C following experimental infection of SPF laying turkeys. In: Proceedings of 2005 Turkey Research Review and Avian Pneumovirus Symposium,Oct 5, 2005,Willmar,MN. 2005 CD-ROM.
SEQUENCE ANALYSIS OF THE TOLL-LIKE RECEPTOR 7 FROM GALLINACEOUS AND NON-GALLINACEOUS SPECIES - (Abstract)
Kapczynski, D.R. 2005. Sequence analysis of the toll-like receptor 7 from gallinaceous and non-gallinaceous species. World Poultry Science Association Proceedings. p. 73.
PANCREATIC PATHOLOGY IN CHICKENS, TURKEYS, AND PIGEONS EXPERIMENTALLY INFECTED WITH NEWCASTLE DISEASE VIRUSES OF DIFFERENT VIRULENCE - (Abstract)
Wakamatsu, N., King, D.J., Seal, B.S., Kapczynski, D.R., Armstrong, K.R., Stewart, M.J., Brown, C.C. 2005. Pancreatic pathology in chickens, turkeys, and pigeons experimentally infected with newcastle disease viruses of different virulence [abstract]. American College of Veterinary Pathologists Abstracts. 42(5)136.
RT-PCR DETECTION OF AVIAN PNEUMOVIRUS STORED ON FTA INDICATING CLASSIC CARD - (Abstract)
Thayer, S.G., Kapczynski, D.R., Senne, D., Moscoso, H., Hofacre, C. 2005. Rt-pcr detection of avian pneumovirus stored on fta indicating classic card. In: Proceedings of the American Association of Avian Pathologists, July 16-20, 2005, Minneapolis, Minnesota. p.77.
EXPERIMENTAL INFECTION OF SPF LAYING TURKEYS WITH AVIAN PNEUMOVIRUS SUBTYPE C: POSSIBLE ROLE OF VERTICAL TRANSMISSION - (Abstract)
Kapczynski, D.R. 2005. Experimental infection of spf laying turkeys with avian pneumovirus subtype c: possible role of vertical transmission. In:Proceedings of the American Association of Avian Pathologists, July 16-20, 2005, Minneasplis, Minnesota. p.34.
EXOTIC NEWCASTLE DISEASE CONJUNCTIVITIS IN A VETERINARY STUDENT - (Abstract)
Richardson, J., Slemons, R., Swayne, D.E., Kapczynski, D.R., King, D.J., Katz, J., Nguyen, D. 2005. Exotic Newcastle disease conjunctivitis in a veterinary student [abstract]. Proceedings of the North Central Avian Disease Conference. p.62-63.
HIGHLY VIRULENT EXOTIC NEWCASTLE DISEASE VIRUS STIMULATES DIFFERENTIAL CYTOKINE GENE EXPRESSION IN CHICKEN SPLENOCYTES FROM LOW VIRULENT LASOTA STRAIN - (Abstract)
Kapczynski, D.R., Holt, P.S. 2005. Highly virulent exotic Newcastle disease virus stimulates differential cytokine gene expression in chicken splenocytes from low virulent LaSota strain [abstract]. Western Poultry Disease Conference. p. 43-45.
MODFICATIONS OF THE OFFICIAL REAL TIME REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION (RRT PCR) ASSAY FOR THE DETECTION OF VIRULENT NEWCASTLE DISEASE IN CLINICAL SPECIMENS - (Abstract)
Pedersen, J.C., Senne, D.A., Suarez, D.L., King, D.J., Kapczynski, D.R., Panigrahy, B. 2005. Modfications of the official real time reverse transcriptase polymerase chain reaction (rrt pcr) assay for the detection of virulent newcastle disease in clinical specimens [abstract]. North Central Avian Disease Conference. p.67.
NP, PB1 and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens - (Peer Reviewed Journal)
Wasilenko, J.L., Lee, C., Sarmento, L., Spackman, E., Kapczynski, D.R., Suarez, D.L., Pantin Jackwood, M.J. 2008. NP, PB1 and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens. Journal of Virology. 82(9):4544-4553.
FUNCTIONAL CHARACTERIZATION AND PHYLOGENETIC COMPARISON OF THE CHICKEN TOLL-LIKE RECEPTOR 7 - (Abstract)
Kapczynski, D.R., Philbin, V.J., Smith, A.L., Holt, P.S. 2005. Functional characterization and phylogenetic comparison of the chicken toll-like receptor 7 [abstract]. American Association of Avian Pathologists. p.56.
CONTRASTING RESULTS FROM MOLECULAR AND BIOLOGICAL PATHOGENICITY ASSAYS OF NEWCASTLE DISEASE VIRUS ISOLATE IOWA 1519 - (Abstract)
King, D.J., Kapczynski, D.R., Afonso, C.L., Piacenti, A. 2005. Contrasting results from molecular and biological pathogenicity assays of newcastle disease virus isolate Iowa 1519 [abstract]. American Association of Avian Pathologists, p.33.
USE OF A MULTIPLEX RT-PCR TO DIFFERENTIATE LENTOGENIC NDV FROM END - (Abstract)
Sellers, H.S., Linnemann, E.G., Kapczynski, D.R. 2005. Use of a multiplex RT-PCR to differentiate lentogenic NDV from END [abstract]. American Association of Avian Pathologists. p. 32.
TWO BURSAL, B-CELL SUBPOPULATIONS WITH DIFFERENT FLOW CYTOMETRY PROFILES FOLLOWING IBDV INFECTION - (Abstract)
Petkov, D.I., Linnemann, E.G., Kapczynski, D.R., Sellers, H.S. 2005. Two bursal, b-cell subpopulations with different flow cytometry profiles following ibdv infection. American Association of Avian Pathologists. p.59.
PROTECTION OF CHICKENS AGAINST OVERT CLINICAL DISEASE AND DETERMINATION OF VIRAL SHEDDING FOLLOWING VACCINATION WITH COMMERIALLY AVAILABLE NEWCASTLE DISEASE VIRUS...FROM THE CALIFORNIA 2002 EXOTIC NEWCASTLE DISEASE OUTBREAK - (Peer Reviewed Journal)
Kapczynski, D.R., King, D.J. 2005. Protection of chickens against overt clinical disease and determination of viral shedding following vaccination with commerially available newcastle disease virus...from the california 2002 exotic newcastle disease outbreak. Vaccine. 23(26):3424-3433.
PHYLOGENETIC ANALYSIS OF THE SIGMA 2 PROTEIN GENE OF TURKEY REOVIRUSES - (Peer Reviewed Journal)
Sellers, H.S., Linnemann, E.G., Pereira, L., Kapczynski, D.R. 2005. Phylogenetic analysis of the sigma 2 protein gene of turkey reoviruses. Avian Diseases. 48:651-7.
MODIFICATIONS OF THE OFFICIAL REAL-TIME REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION (RRT-PCR) ASSAY FOR THE DETECTION OF VIRULENT NEWCASTLE DISEASE IN CLINICAL SPECIMENS - (Abstract)
Pedersen, J.C., Senne, D.A., Suarez, D.L., King, D.J., Kapczynski, D.R., Panigrahy, B. 2005. Modifications of the official real-time reverse transcriptase polymerase chain reaction (rrt-pcr) assay for the detection of virulent newcastle disease in clinical specimens [abstract]. Western Poultry Disease Conference. p.40.
GENOMIC SEQUENCES OF LOW VIRULENCE AVIAN PARAMYXOVIRUS 1 (NEWCASTLE DISEASE VIRUS) ISOLATES OBTAINED FROM LIVE-BIRD MARKETS IN NORTH AMERICA NOT RELATED TO COMMONLY UTILIZED COMMERCIAL VACCINE STRAINS - (Peer Reviewed Journal)
Seal, B.S., Wise, M., Pedersen, J.C., Senne, D.A., Alvarez, R., Scott, M.A., King, D.J., Yu, Q., Kapczynski, D.R. 2005. Genomic sequences of low virulence avian paramyxovirus 1 (Newcastle disease virus) isolates obtained from live-bird markets in North America not related to commonly utilized commercial vaccine strains. Veterinary Microbiology. 106(1-2):7-16.
COMPARISON OF SUSCEPTIBILITY AND IMMUNITY FOLLOWING VACCINATION TO THE 2002-03 CALIFORNIA VIRULENT NEWCASTLE DISEASE VIRUS (VNDV) BETWEEN COMMERCIAL AND SPF TURKEYS - (Abstract)
Kapczynski, D.R., King, D.J. 2005. Comparison of susceptibility and immunity following vaccination to the 2002-03 california virulent newcastle disease virus (vndv) between commercial and spf turkeys. Western Poultry Disease Conference. p.43.
INFECTIOUS BURSAL DISEASE VIRUS FULL-LENGTH SEQUENCE ANALYSIS - (Abstract)
Petkov, D.I., Linnemann, E., Kapczynski, D.R., Sellers, H.S. 2005. Infectious bursal disease virus full-length sequence analysis. Proceedings of Southern Conference on Avian Diseases. p. 32.
EVALUATION OF THE IMMUNOLOGICAL RESPONSE TO IBDV BY FLOW CYTOMETRY AND ELISA - (Abstract)
Petkov, D.I., Kapczynski, D.R., Sellers, H.S. 2005. Evaluation of the immunological response to ibdv by flow cytometry and elisa. In:Proceedings of Southern Conference on Avian Diseases, January 24-25, 2005, Atlanta, Georgia. p.34.
MULTIPLEX REAL-TIME RT-PCR FOR THE DETECTION OF THREE VIRUSES ASSOCIATED WITH POULT ENTERITIS COMPLEX: TURKEY ASTROVIRUS, TURKEY CORONAVIRUS, AND TURKEY REOVIRUS - (Peer Reviewed Journal)
Spackman, E., Kapczynski, D.R., Sellers, H., 2005. Multiplex real-time rt-pcr for the detection of three viruses associated with poult enteritis complex: turkey astrovirus, turkey coronavirus, and turkey reovirus. Avian Diseases. 49:86-91.
CHICKEN INTERFERON-GAMMA MONOCLONAL ANTIBODIES AND THEIR APPLICATION IN A FLOW CYTOMETRIC MICROSPHERE ASSAY - (Abstract)
Kapczynski, D.R., Terrence, M.T. 2004. Chicken Interferon-Gamma Monoclonal Antibodies and Their Application in a Flow Cytometric Microsphere Assay. Avian Immunology Research Group Abstract.
PATHOLOGIC FINDINGS IN CHICKENS, TURKEYS, AND PIGEONS EXPERIMENTALLY INFECTED WITH EXOTIC NEWCASTLE DISEASE VIRUS FROM AN OUTBREAK IN CALIFORNIA DURING 2002-2003 - (Abstract)
Wakamatsu, N., Brown, C., Kapczynski, D.R., Seal, B.S., King, D.J. 2004. Pathologic findings in chickens, turkeys, and pigeons experimentally infected with exotic newcastle disease virus from an outbreak in california during 2002-2003 [abstract]. Veterinary Pathology. 41(5):581.
EVALUATION OF COMMERCIAL LIVE AND INACTIVATED NEWCASTLE DISEASE VIRUS (B1) VACCINES FOR PROTECTION OF CHICKENS AND TURKEYS AGAINST THE 2002-03 CALIFORNIA EXOTIC NEWCASTLE DISEASE VIRUS - (Trade Journal)
Kapczynski, D.R., King, D.J. 2004. Evaluation of Commercial Live And Inactivated Newcastle Disease Virus (B1) Vaccines For Protection Of Chickens And Turkeys Against The 2002-03 California Exotic Newcastle Disease Virus. Avian Insight, A Lohmann Animal Health International News Brief, V.3, p 1-3.
EVALUATION OF THE HUMORAL IMMUNE RESPONSE TO IBDV IN SPECIFIC-PATHOGENIC-FREE CHICKENS USING FLOW CYTOMETRY ANALYSIS AND ELISA - (Abstract)
Petlov, D.I., Linnemann, E.G., Kapczynski, D.R., Sellers, H.S. 2004. Evaluation of the humoral immune response to ibdv in specific-pathogenic-free chickens using flow cytometry analysis and elisa. In:Proceedings of the American Association of Avian Pathologists, July 24-28, 2004, Philadelphia, Pennsylvania. CDROM.
SEROLOGICAL CROSS-REACTIVITY AMONG MEMBERS OF THE METAPNEUMOVIRINAE GENUS - (Peer Reviewed Journal)
Alvarez, R., Jones, L.P., Seal, B.S., Kapczynski, D.R., Tripp, R.A. 2004. Serological cross-reactivity among members of the metapneumovirinae genus. Virus Research. 105:67-73.
CONTROL OF NEWCASTLE DISEASE BY VACCINATION - (Proceedings/Symposium)
Senne, D.A., King, D.J., Kapczynski, D.R. 2004. Control of newcastle disease by vaccination. Developments in Biologicals (Basel). 119:165-170.
DEVELOPMENT OF A VIROSOME VACCINE FOR PROTECTING TURKEY POULTS AGAINST SUBTYPE C AVIAN METAPNEUMOVIRUS - (Abstract)
Kapczynski, D.R. 2004. Development of a virosome vaccine for protecting turkey poults against subtype c avian metapneumovirus. In:Proceedings of the American Association of Avian Pathologists., July 24-28, 2004, Philadelphia, Pennsylvania. 2004 CDROM
APOPTOSIS OF PANCREATIC EXOCRINE CELLS IN BIRDS INFECTED WITH NEWCASTLE DISEASE VIRUSES - (Abstract)
Armstrong, K.R., Wakamatsu, N., King, D.J., Seal, B.S., Kapczynski, D.R., Brown, C.C. 2004. Apoptosis of pancreatic exocrine cells in birds infected with newcastle disease viruses. Meeting Abstract.
THE SUSCEPTIBILITY OF NON-VACCINATED AND PMV-1 VACCINATED RACING PIGEONS TO INFECTION WITH EXOTIC NEWCASTLE DISEASE (END) VIRUS ISOLATE DURING THE 2002-2003 END OUTBREAK - (Abstract)
King, D.J., Kapczynski, D.R., Wakamatsu, N., Wise, M. 2004. The susceptibility of non-vaccinated and pmv-1 vaccinated racing pigeons to infection with exotic newcastle disease (end) virus isolate during the 2002-2003 end outbreak. American Association of Avian Pathologists.
EXPERIMENTAL VIRULENCE ASSESSMENT OF EXOTIC NEWCASTLE DISEASE VIRUS FROM AN OUTBREAK IN CALIFORNIA DURING 2002-2003 FOR CHICKENS, TURKEYS, AND PIGEONS - (Abstract)
Nobuko, W., Brown, C., Kapczynski, D.R., Seal, B.S., King, D.J. 2004. Experimental virulence assessment of exotic newcastle disease virus from an outbreak in california during 2002-2003 for chickens, turkeys, and pigeons. American Association of Avian Pathologists.
VIROSOME VACCINATION AGAINST AVIAN METAPNEUMOVIRUS DECREASES CLINICAL SIGNS OF DISEASE AND VIRAL LOAD FOLLOWING CHALLENGE - (Proceedings/Symposium)
Kapczynski, D.R. 2004. Virosome vaccination against avian metapneumovirus decreases clinical signs of disease and viral load following challenge. In: Proceedings of the IV International Symposium on Avian Corona-and Pneumovirus Infections, June 20-23, 2004, Giessen, Germany. p.372-381.
DEVELOPMENT OF A VIROSOME VACCINE FOR PROTECTION IN TURKEYS AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C - (Abstract)
Kapczynski, D.R. 2004. Development of a virosome vaccine for protection in turkeys against avian metapneumovirus subtype c. Symposium on Avian Pneumovirus. P.372.
VACCINE PROTECTION IN CHICKENS AND TURKEYS AGAINST THE 2002 EXOTIC NEWCASTLE DISEASE VIRUS - (Proceedings/Symposium)
Kapczynski, D.R., King, D.J. 2004. Vaccine Protection In Chickens And Turkeys Against The 2002 Exotic Newcastle Disease Virus. Western Poultry Disease Conference p.64-65, 2004.
COMPARISON OF SUSCEPTIBILITY AND IMMUNITY FOLLOWING VACCINATION TO THE 2002-03 CALIFORNIA VIRULENT NEWCASTLE DISEASE VIRUS (VNDV) BETWEEN COMMERCIAL AND SPF TURKEYS - (Proceedings/Symposium)
Kapczynski, D.R., King, D.J. 2005. Comparison of susceptibility and immunity following vaccination to the 2002-03 California virulent Newcastle disease virus (vNDV) between commercial and SPF turkeys [abstract]. Western Poultry Disease Conference. p. 43-45.
EVALUATION OF A COMMERCIAL AVIAN INFLUENZA (H7N2) VACCINE FOR PROTECTION IN TURKEYS AGAINST AN AVIAN INFLUENZA VIRUS (H7N2) ISOLATED FROM TURKEYS IN VIRGINIA DURING 2002 - (Abstract)
Tumpey, T., Kapczynski, D.R., Swayne, D.E. 2004. Evaluation of a Commercial Avian Influenza (H7N2) Vaccine for Protection in Turkeys Against an Avian Influenza Virus (H7N2) Isolated From Turkeys in Virginia During 2002. Immunology Research Workshop.
DEVELOPMENT OF A VIROSOME VACCINE FOR PROTECTION IN TURKEYS AGAINST AVIAN METAPNEUMOVIRUS SUBTYPE C - (Peer Reviewed Journal)
Kapczynski, D.R. 2004. Development of A Virosome Vaccine For Protection In Turkeys Against Avian Metapneumovirus Subtype C. Avian Diseases v.48, p.332-343. 2004.
EVALUATION OF A COMMERCIAL AVIAN INFLUENZA (H7N2) VACCINE FOR PROTECTION IN TURKEYS AGAINST AN AVIAN INFLUENZA VIRUS (H7N2) ISOLATED FROM TURKEYS IN VIRGINIA DURING 2002. - (Peer Reviewed Journal)
Tumpey, T., Kapczynski, D.R., Swayne, D.E. 2004. Evaluation Of A Commercial Avian Influenza (H7N2) Vaccine For Protection In Turkeys Against An Avian Influenza Virus (H7N2) Isolated From Turkeys In Virginia During 2002.. Avian Diseases 48(1):167-176, 2004.
NDV VACCINES - FIELD VERSUS EXPERIMENTAL STUDIES - (Proceedings/Symposium)
Kapczynski, D.R., King, D.J. 2004. NDV Vaccines - Field Versus Experimental Studies. United States Animal Health Association Proceedings, p.520-521, 2003.
DEVELOPMENT OF AN INACTIVATED NEWCASTLE DISEASE VIROSOME VACCINE THAT PROTECTS AGAINST CHALLENGE FROM VELOGENIC TEXAS GB - (Abstract)
Kapczynski, D.R., Tumpey, T. 2003. Development of an inactivated newcastle disease virosome vaccine that protects against challenge from velogenic texas gb. Immunology Research Workshop.
DEVELOPMENT OF A REAL-TIME REVERSE-TRANSCRIPTION, POLYMERASE CHAIN REACTION FOR DETECTION OF NEWCASTLE DISEASE VIRUS RNA IN CLINICAL SAMPLES - (Peer Reviewed Journal)
Wise, M., Suarez, D.L., Seal, B.S., Janice, P.C., Senne, D.A., King, D.J., Kapczynski, D.R., Spackman, E. Development Of A Real-Time Reverse-Transcription, Polymerase Chain Reaction For Detection Of Newcastle Disease Virus RNA In Clinical Samples. Journal of Clinical Microbiology. Vol. 42, No.1, p329-338. 2004
EVALUATION OF A COMMERCIAL AVIAN INFLUENZA (H7N2) VACCINE FOR PROTECTION IN TURKEYS AGAINST AN AVIAN INFLUENZA VIRUS (H7N2) ISOLATED FROM TURKEYS IN VIRGINIA DURING 2002 - (Trade Journal)
TUMPEY, T., KAPCZYNSKI, D.R., SWAYNE, D.E. EVALUATION OF A COMMERCIAL AVIAN INFLUENZA (H7N2) VACCINE FOR PROTECTION IN TURKEYS AGAINST AN AVIAN INFLUENZA VIRUS (H7N2) ISOLATED FROM TURKEYS IN VIRGINIA DURING 2002. LOHMANN ANIMAL HEALTH NEWSLETTER (Avian Insight 3:1-4), 2003.
IMMUNIZATION OF TURKEYS WITH A DNA VACCINE EXPRESSING EITHER THE F OR N GENE OF AVIAN METAPNEUMOVIRUS - (Peer Reviewed Journal)
Kapczynski, D.R., Sellers, H.S. 2003. Immunization Of Turkeys With A DNA Vaccine Expressing Either the F Or N Gene Of Avian Metapneumovirus. Avian Diseases v.47 p.1376-1383.
NUCLEOTIDE AND PREDICTED AMINO ACID SEQUENCE ANALYSIS OF THE AVIAN METAPNEUMOVIRUS TYPE C CELL ATTACHMENT GLYCOPROTEIN (G) GENE. PHYLOGENETIC ANALYSIS AMONG THE PNEUMOVIRINAE AND MOLECULAR EPIDEMIOLOGY OF U.S. VIRUSES - (Abstract)
Alvarez, R., Lwamba, H.M., Kapczynski, D.R., Njenga, M., Seal, B.S. 2003. Nucleotide and predicted amino acid sequence analysis of the avian metapneumovirus type c cell attachment glycoprotein (g) gene. phylogenetic analysis among the pneumovirinae and molecular epidemiology of u.s. viruses. American Society for Virology Meeting.
VACCINATION EFFORTS WITH VIROSOMES PRODUCED FROM NEWCASTLE DISEASE VIRUS - (Abstract)
Kapczynski, D.R., Tumpey, T. 2003. Vaccination efforts with virosomes produced from newcastle disease virus. Western Poultry Disease Conference.
VACCINATION EFFORTS WITH VIROSOMES PRODUCED FROM NEWCASTLE DISEASE VIRUS - (Proceedings/Symposium)
Kapczynski, D.R., Tumpey, T. 2003. Vaccination Efforts With Virosomes Produced From Newcastle Disease Virus. Western Poultry Disease Conference Proceedings, p.33, 2003.
DEVELOPMENT OF A VIROSOME VACCINE FOR NEWCASTLE DISEASE VIRUS THAT PROTECTS AGAINST LETHAL CHALLENGE - (Peer Reviewed Journal)
KAPCZYNSKI, D.R., TUMPEY, T. DEVELOPMENT OF A VIROSOME VACCINE FOR NEWCASTLE DISEASE VIRUS THAT PROTECTS AGAINST LETHAL CHALLENGE. AVIAN DISEASES. 2003. 47:578-587.
NUCLEOTIDE AND PREDICTED AMINO ACID SEQUENCE ANALYSIS OF THE AVIAN METAPNEUMOVIRUS TYPE C CELL ATTACHMENT GLYCOPROTEIN (G) GENE. PHYLOGENETIC ANALYSIS AMONG THE PNEUMOVIRINAE AND MOLECULAR EPIDEMIOLOGY OF U.S. VIRUSES - (Peer Reviewed Journal)
ALVAREZ, R., LWAMBA, H.M., KAPCZYNSKI, D.R., NJENGA, M., SEAL, B.S. NUCLEOTIDE AND PREDICTED AMINO ACID SEQUENCE ANALYSIS OF THE AVIAN METAPNEUMOVIRUS TYPE C CELL ATTACHMENT GLYCOPROTEIN (G) GENE. PHYLOGENETIC ANALYSIS AMONG THE PNEUMOVIRINAE AND MOLECULAR EPIDEMIOLOGY OF U.S. VIRUSES. JOURNAL OF CLINICAL MICROBIOLOGY. 2003. 1730-1735.
INTRANASAL VACCINATION WITH INACTIVATED AVIAN METAPNEUMOVIRUS VACCINE INDUCES ANTIBODIES WITH DECREASED NEUTRALIZATION CAPABILITY FOLLOWING VIRUS CHALLENGE IN TURKEYS - (Peer Reviewed Journal)
Kapczynski, D.R., Perkins, L., Sellers, H.S. 2002. Intranasal vaccination with inactivated avian metapneumovirus vaccine induces antibodies with decreased neutralization capability following virus challenge in turkeys. Avian Diseases.
DETECTION OF IN OVO INOCULATED INFECTIOUS BRONCHITIS VIRUS BY IN SITU HYBRIDIZATION WITH A RIBOPROBE IN EPITHELIAL CELLS OF THE LUNG AND BURSA - (Peer Reviewed Journal)
Kapczynski, D.R., Sellers, H.S., Rowland, G.N., Jackwood, M.W. 2002. Detection of in Ovo Inoculated Infectious Bronchitis Virus by In Situ Hybridization with a Riboprobe in Epithelial Cells of the Lung and Bursa. Avian Diseases.
IMMUNE FUNCTION FOLLOWING VACCINATION WITH AN INACTIVATED AVIAN PNEUMOVIRUS VACCINE - (Proceedings/Symposium)
Kapczynski, D.R., Tumpey, T. 2002. Immune function following vaccination with an inactivated avian pneumovirus vaccine. Western Poultry Disease Conference.

   
 
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