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Genetic Variation Program
Genetic Variation Program OverviewMost of any one person's DNA, about 99.5 percent, is exactly the same as any unrelated person's DNA. Differences in the sequence of DNA among individuals are called genetic variation. Genetic variation explains some of the differences among people, such as eye color and blood group. Genetic variation also plays a role in whether a person has a higher or lower risk for getting particular diseases. Single gene differences in individuals account for some traits and diseases, such as the ABO blood group, cystic fibrosis and sickle cell disease. More complex interrelationships among multiple genes and the environment are responsible for many common diseases, such as diabetes, cancer, stroke, Alzheimer's disease, Parkinson's disease, depression, alcoholism, heart disease, arthritis and asthma. The Genetic Variation program supports research on genetic variation and how it relates to diseases, responses to drugs and environmental factors. The Genetic Variation Program supports research aimed at:
Genetic Variation Program Related InformationResource for Discovering DNA Polymorphisms
NCBI Database for SNPs, dbSNP [ncbi.nom.nih.gov]
Genetic Variation Program Meeting ReportsAugust 3-4, 2004 July 18-19, 2001 SNP Meeting: June 7-8, 1999 March 31-April 1, 1997 December 8-9, 1997
Genetic Variation Program Funding OpportunitiesPA-97-044: Technologies for Genomic Mapping, Sequencing and Analysis RFA HG-98-001: Methods for Discovering and Scoring Single Nucleotide Polymorphisms (EXPIRED)
NIGMS PA-99-016 [grants2.nih.gov]: Mechanisms Underlying Individual Variations in Drug Responses. NIGMS PA-98-078 [grants.nih.gov]: Genetic Architecture of Complex Phenotypes. NIMH RFA MH-98-017 [grants.nih.gov]: Quantitative Methods to Map Genes for Complex Disease (Expired) Centers of Excellence in Genomic Science (CEGS) Small Business Funding Opportunities [grants.nih.gov]: Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) program information.
Genetic Variation Program StaffProgram Directors Jean McEwen, Ph.D. Address
Last Reviewed: September 11, 2008 |
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