Established in 1846, Fort Brown housed troops during Mexican-American War, defended border; changed hands during Civil War. Noted for work of William C. Gorgas, later U.S. Army Surgeon General, whose studies led to eventual control of yellow fever. First developed into large military reservation and was an active post until the end of World War II. Original hospital now administration building of Texas Southmost College. Other remaining buildings include cavalry barracks, medical lab, guardhouse, and morgue. International Blvd. and May St. near Gateway International Bridge.