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LATEST: Molecular Systems Biology 2010 Impact Factor is 9.667 (2010 Journal Citation Reports®, Thomson Reuters, 2011)
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A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
By characterizing dynamic changes in yeast protein abundance following osmotic shock, this study shows that the correlation between protein and mRNA differs for transcripts that increase versus decrease in abundance, and reveals physiological reasons for these differences.
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Top 10 downloads
- Cell-to-cell variability of alternative RNA splicing
- Predicting selective drug targets in cancer through metabolic networks
- A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
- Microbial laboratory evolution in the era of genome-scale science
- Phosphorylation network rewiring by gene duplication
- Full top 10 list of downloads
Research Articles
A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
M Violet Lee, Scott E Topper, Shane L Hubler, James Hose, Craig D Wenger, Joshua J Coon and Audrey P Gasch
doi:10.1038/msb.2011.48
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Absolute quantification of microbial proteomes at different states by directed mass spectrometry
Alexander Schmidt, Martin Beck, Johan Malmström, Henry Lam, Manfred Claassen, David Campbell and Ruedi Aebersold
doi:10.1038/msb.2011.37
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Quantification of mRNA and protein and integration with protein turnover in a bacterium
Tobias Maier, Alexander Schmidt, Marc Güell, Sebastian Kühner, Anne-Claude Gavin, Ruedi Aebersold and Luis Serrano
doi:10.1038/msb.2011.38
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs
Frank Wessely, Martin Bartl, Reinhard Guthke, Pu Li, Stefan Schuster and Christoph Kaleta
doi:10.1038/msb.2011.46
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
A pharmacogenomic method for individualized prediction of drug sensitivity
Adam L Cohen, Raffaella Soldi, Haiyu Zhang, Adam M Gustafson, Ryan Wilcox, Bryan E Welm, Jeffrey T Chang, Evan Johnson, Avrum Spira, Stefanie S Jeffrey and Andrea H Bild
doi:10.1038/msb.2011.47
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range
Julie Bachmann, Andreas Raue, Marcel Schilling, Martin E Böhm, Clemens Kreutz, Daniel Kaschek, Hauke Busch, Norbert Gretz, Wolf D Lehmann, Jens Timmer and Ursula Klingmüller
doi:10.1038/msb.2011.50
Published online: 19 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Cell-to-cell variability of alternative RNA splicing
Zeev Waks, Allon M Klein and Pamela A Silver
doi:10.1038/msb.2011.32
Published online: 5 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
The auxin signalling network translates dynamic input into robust patterning at the shoot apex
Teva Vernoux, Géraldine Brunoud, Etienne Farcot, Valérie Morin, Hilde Van den Daele, Jonathan Legrand, Marina Oliva, Pradeep Das, Antoine Larrieu, Darren Wells, Yann Guédon, Lynne Armitage, Franck Picard, Soazig Guyomarc'h, Coralie Cellier, Geraint Parry, Rachil Koumproglou, John H Doonan, Mark Estelle, Christophe Godin, Stefan Kepinski, Malcolm Bennett, Lieven De Veylder and Jan Traas
doi:10.1038/msb.2011.39
Published online: 5 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes
Kenneth K Lee, Mihaela E Sardiu, Selene K Swanson, Joshua M Gilmore, Michael Torok, Patrick A Grant, Laurence Florens, Jerry L Workman and Michael P Washburn
doi:10.1038/msb.2011.40
Published online: 5 July 2011
Synopsis | Full Text | PDF | Supp. Inf. | Review Process
Report
Phosphorylation network rewiring by gene duplication
Luca Freschi, Mathieu Courcelles, Pierre Thibault, Stephen W Michnick and Christian R Landry
doi:10.1038/msb.2011.43
Published online: 5 July 2011
Full Text | PDF | Supp. Inf. | Review Process
Review
Microbial laboratory evolution in the era of genome-scale science
Tom M Conrad, Nathan E Lewis and Bernhard Ø Palsson
doi:10.1038/msb.2011.42
Published online: 5 July 2011
Perspective
Retrieval, alignment, and clustering of computational models based on semantic annotations
Marvin Schulz, Falko Krause, Nicolas Le Novère, Edda Klipp & Wolfram Liebermeister
doi:10.1038/msb.2011.41
Published online: 19 July 2011
News and Views
Alternative splicing variability: exactly how similar are two identical cells?
Rhonda J Perriman and Manuel Ares, Jr
doi:10.1038/msb.2011.44
Published online: 5 July 2011
More systems biology from NPG & EMBO
A selection of relevant articles hosted by Nature Publishing Group are listed below. More articles can be found on the Systems biology Subject Area page.
