Guenter W. Gross, Ph.D.

Regents Professor and Director of the Center for Network Neuroscience

Office: SRB 120A
Phone: (940)565-3615
E-mail: gwgross@unt.edu

Laboratory: Center for Network Neuroscience

GENERAL RESEARCH DOMAIN: Cellular and Network Neurophysiology
SPECIFIC RESEARCH AREAS:
(1) Internal Dynamics of Small Mammalian Nerve Cell Networks:
pattern generation, pattern recognition and storage; fault tolerance.
(2) Cell-Electrode Coupling and Cell Adhesion to Artificial Surfaces.
(3) Multichannel Recording and Life-Support Technology for Cell Culture.
(4) Theory of Network Self-Organization and network-network interactions.
(5) Applied Neuronal Network Dynamics to
  (a) Neurotoxicology & Pharmacology
  (b) Drug Development
  (c) Tissue-Based Biosensors
  (d) Pharmaceutical Biotechnology: Development of multinetwork platforms for rapid assays.
ACTIVE COLLABORATIONS
Plexon Inc., Dallas, TX. Development and testing of data acquisition and processing hardware and software. Development of 8-network high throughput recording/assay platforms.
Los Alamos National Laboratory, N. M., Dr. Luis Bettencourt, Computer & Computational Sciences Division, CCS-3/Modeling, Algorithms & Informatics. Internal network dynamics, origins of spontaneous activity, network self-organization, methods for pattern quantification .
Technical University of Munich, Germany; Professor Dr. Bernhard Wolf. Integrated pH, oxygen, and impedance sensors for networks in culture; magnetic stimulation of neurons in culture with emphasis on applications to pain management..
UT Southwestern Medical School, Dallas, Dr. Edward Keefer, Department of Plastic Surgery,
Electrode modification with carbon nanotubes; interaction of nanotubes with glial and neuronal membranes.
University of Rostock, Germany, Professor Dieter G. Weiss, Department of Zoology.
Nerve cell networks on microelectrode arrays: system validation via reproducibility of histiotypic pharmacological responses.
Environmental Protection Agency, Research Triangle , N. C.,
Dr. Timothy Shafer, Department of Neurotoxicology
Pyrethroid neurotoxicity
Development of high throughput multinetwork assay platforms
University of North Texas, Department of Speech and Hearing Sciences
Dr. Kamakshi Gopal
Pharmacology and toxicology of auditory cortex networks
Dr. Ernest Moore
Development of cell culture models on microelectrode arrays of the zebra fish auditory systems
University of North Texas, Department of Physics
Dr. Paolo Grigolini, Dr. Jacek Kowalski, Dr. Dell McDaniel
Theoretical network dynamics; complex networks; self-organization of dynamic systems
University of North Texas, Department of Biological Sciences
Dr, Duane Huggett
Environmental Toxicology and Pharmacokinetics: joint application of molecular biology, biochemistry and network electrophysiology to determine mechanisms of Environmental toxicants.
University of Texas at Arlington, Department of Bioengineering
Dr. Mario Romero
Generation of spinal reflex circuits in vitro on microelectrode arrays with application to drug development ands regeneration.