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stain of diphtheria |
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CDC describes diphtheria as "an upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose". Diphtheria is a rapidly developing, acute, febrile infection which involves both local and systemic pathology. A local lesion develops in the upper respiratory tract and involves necrotic injury to epithelial cells. As a result of this injury, blood plasma leaks into the area and a fibrin network forms which is interlaced with with rapidly-growing C. diphtheriae cells.
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FDA Talk Paper| | First Combination Vaccine Approved to Help Protect Adolescents Against Whooping Cough
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ALARACT PDF 21 Jan 06| | ADOPTION OF NEW TETANUS-DIPHTHERIA-ACELLULAR PERTUSSIS (TDAP)
VACCINE
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MMQC-06-1289| | SANOFI PASTEUR TEMPORARY SHORTAGE OF ADACEL® VACCINE / UPDATED INFORMATION BULLETIN
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MMQC-06-1235| | SANOFI PASTEUR / DECAVAC® VACCINE (TETANUS & DIPHTHERIA TOXOID) / AMERISOURCE BERGEN VOLUNTARY RECALL
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MMQC-06-1219| | SANOFI PASTEUR DECAVAC (DIPHTHERIA TOXOID, ADSORBED / TETANUS TOXOID) / VOLUNTARY RECALL / DSCP 06-124
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