Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD) - Tabular View

This Tabular View shows the required WHO registration data elements as marked by ^†

Tracking Information

First Received Date ^†

April 30, 2009

Last Updated Date

April 30, 2009

Start Date ^†

November 2008

Current Primary Outcome Measures ^†

PTSD symptoms [ Time Frame: pretreatment, weekly during treatment, posttreatment, followup ] [ Designated as safety issue: No ]

Original Primary Outcome Measures ^†

Same as current

Change History

No Changes Posted

Current Secondary Outcome Measures ^†

General psychiatric symptoms [ Time Frame: pretreatment, weekly during treatment, postttreatment, followup ] [ Designated as safety issue: No ]

Original Secondary Outcome Measures ^†

Same as current

Descriptive Information

Brief Title ^†

Comparing Imaginal Exposure and Imagery Rescripting in Treatment of Posttraumatic Stress Disorder (PTSD)

Official Title ^†

Comparing Imaginal Exposure (IE) and Imagery Rescripting and Reprocessing Therapy (IRRT) in the Treatment of Posttraumatic Stress Disorder (PTSD)

Brief Summary

The outcome of trauma treatment (Posttraumatic Stress Disorder - PTSD) may be influenced by which emotions that are predominant among current symptoms, e.g. fear, anger, guilt, shame. Different treatment procedures for processing traumatic memories may resolve different emotions. This study compares two different treatment procedures of working with trauma memories in PTSD treatment (namely, Imaginal Exposure and Imagery Rescripting) in order to test this.

Detailed Description

The main objectives of this study are:

To assess the relative efficacy of the two procedures in inpatient treatment for PTSD
To assess whether the predominant emotions in the traumatic memories moderate the outcome of the different procedures
To assess whether theory-derived constructs mediate outcome and whether the mediating relationships are different in the two treatments
To provide a theoretical account of the two models
To psychometrically evaluate 3 new measures

Study Phase

Study Type ^†

Interventional

Study Design ^†

Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study

Condition ^†

Posttraumatic Stress Disorder

Intervention ^†

Behavioral: Imaginal exposure
Behavioral: Imagery rescripting

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^†

Enrolling by invitation

Estimated Enrollment ^†

Estimated Completion Date

November 2012

Estimated Primary Completion Date

November 2012 (final data collection date for primary outcome measure)

Eligibility Criteria ^†

Inclusion Criteria:

DSM-IV diagnosis of PTSD identified as primary diagnosis
Accepts withdrawal of all psychotropic medication

Exclusion Criteria:

Extensive dissociative symptoms or current psychosis,
Current suicidal risk,
Extensive current substance or alcohol abuse, or
Ongoing trauma

Gender

Both

Ages

20 Years to 65 Years

Accepts Healthy Volunteers

Contacts ^††

Location Countries ^†

Norway

Expanded Access Status

Administrative Information

NCT ID ^†

NCT00891098

Responsible Party

Asle Hoffart, PhD., Modum Bad

Secondary IDs ^††

Study Sponsor ^†

Modum Bad

Collaborators ^††

University of Oslo

Investigators ^†

Study Chair:

Asle Hoffart, PhD

Modum Bad and University of Oslo

Information Provided By

Modum Bad

Verification Date

April 2009

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.