Figure 1. Analytic framework

A flow chart depicts the analytic framework and incorporates the five key questions for this review. Go to [D] Text Description for details.

Key questions:

  1. Does screening for gestational diabetes lead to a reduction in perinatal morbidity and mortality for mother or infant? A) After 24 weeks' gestation?
  2. What are the sensitivities, specificities, reliabilities, and yields of current screening tests for gestational diabetes? A) After 24 weeks' gestation? B) During the first trimester and up to 24 weeks' gestation?
  3. Does treatment of gestational diabetes lead to reduction in perinatal morbidity and mortality for mother or infant? A) After 24 weeks' gestation? B) During the first trimester and up to 24 weeks' gestation?
  4. What are the adverse effects associated with screening for gestational diabetes?
  5. What are the adverse effects associated with treatment of gestational diabetes?

Note: GDM = gestational diabetes mellitus; NICU = neonatal intensive care unit.

[D] Select for Text Description.

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