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Structures
Background:
Four Levels of Structure
Lab Techniques: How are Structures Resolved?
Protein Data Bank (PDB)
Molecular Modeling Database (MMDB)
3-Dimensional View of Structure Record
Searching for Structures
Fewer Structures than Protein Sequences
"Front Doors" and "Back Doors" for Retrieving Structures
Using the Front Doors (Demo: P53 Tumor Suppressor Protein)
Understanding the Output: Structure Record Summary
Cn3D ("See in 3-D") Viewing Software
Using the Back Doors (Finding structures in the absence of an exact query match)
Hands-On
Demonstration Exercise: MLH1
(Finding structures related to the human MLH1 gene product)
Mastery Exercise: PER2
(Finding structures related to the human period (PER2) gene product)
Additional User Questions
Structure News:
PubChem Project: Small Molecules
References
Structures
Revised 11/06/2007
