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yttrium Y 90 anti-CD45 monoclonal antibody AHN-12 A radioimmunoconjugate comprised of the monoclonal antibody AHN-12 conjugated to the radioisotope yttrium 90 with potential radioimmunotherapeutic activity. Yttrium Y 90 monoclonal antibody AHN-12 binds to the tyrosine phosphatase CD45, expressed on the surface of normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.
Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Abbreviation: | ![](https://webarchive.library.unt.edu/eot2008/20090509163019im_/http://www.cancer.gov/images/spacer.gif) | Y 90 AHN-12 | | ![](https://webarchive.library.unt.edu/eot2008/20090509163019im_/http://www.cancer.gov/images/spacer.gif) |
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