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monoclonal antibody Lym-1
A murine IgG2a monoclonal antibody directed against the HLA-Dr10 protein, a cell surface marker present on over eighty percent of lymphoma cells. When conjugated with a radioactive isotope, Lym-1 monoclonal antibody selectively transports the cytotoxic radioisotope to HLA-Dr10-expressing tumor cells, thereby sparing healthy B-cells and normal tissues. This agent also mediates antibody-dependent cytotoxicity thereby promoting Raji B-lymphoid cell lysis by human neutrophils. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | IgG2a murine monoclonal antibody Lym-1
Lym-1
monoclonal antibody Lym-1, IgG2a murine | | | | Abbreviation: | | MOAB Lym-1 | | |
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