New Information about Taking Ibuprofen and Aspirin Together

If your doctor told you to take aspirin to help prevent a heart attack, you need to know that taking ibuprofen at the same time, for pain relief, may interfere with the benefits of aspirin for the heart. It is all right to use them together, but the FDA recommends that you contact your doctor for more information on the timing of when to take these two medicines, so that both medicines can be effective.

This information reflects FDA’s current analysis of data available to FDA concerning this drug.
FDA intends to update this sheet when additional information or analyses become available.

Ibuprofen, non-prescription (over-the-counter)

Ibuprofen Drug Facts

• Drug Facts Label [PDF] or [HTML]

Healthcare Professional Information

• Healthcare Professional Sheet [PDF] or [HTML]

• Science Background Paper: Concomitant Use of Ibuprofen and Aspirin: Potential for Attenuation of the Anti-Platelet Effect of Aspirin (9/8/2006)[PDF]