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Clinical Trial Results

Summaries of Newsworthy Clinical Trial Results

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Related Pages
Ovarian Cancer Home Page 1
NCI's gateway for information about ovarian cancer.

Search for Clinical Trials 2
NCI's PDQ® registry of cancer clinical trials.
Ovarian Cancer Trial Results
1.  Removal of Ovaries and Fallopian Tubes Cuts Cancer Risk for BRCA1/2 Carriers 3
(Posted: 02/24/2009) - Surgery that removes the ovaries and fallopian tubes is one of the most effective ways to decrease a woman's risk of breast and gynecologic cancer if she carries a BRCA1 or BRCA2 gene mutation, according to the Jan. 21, 2009, Journal of the National Cancer Institute.

2.  Ultrasound Expertise Important in the Diagnosis of Ovarian Cancer 4
(Posted: 02/25/2008) - Improving the quality of diagnostic ultrasound scans could significantly reduce unnecessary surgeries in women with suspected ovarian cancer who, in fact, have benign disease, according to the February 2008 issue of the Lancet Oncology.

3.  Impact of Intraperitoneal Chemotherapy on Quality of Life During Ovarian Cancer Treatment 5
(Posted: 02/14/2007) - Women with ovarian cancer treated with intraperitoneal (IP)chemotherapy reported more side effects and a lower quality of life during their treatment compared to women receiving intravenous chemotherapy. However, at the end of one year, only neurological symptoms remained worse for the IP group, according to the Feb. 1, 2007, Journal of Clinical Oncology.

4.  Review Confirms Effectiveness of Intraperitoneal Chemotherapy for Advanced Ovarian Cancer 6
(Posted: 12/18/2006) - Combined data from 60 randomized clinical trials of advanced ovarian cancer showed that multidrug chemotherapy using a platinum-based drug and a taxane-based drug delivered directly into the abdomen (intraperitoneal chemotherapy) can help women survive a median of 5.5 years, according to the Nov. 15, 2006, Journal of the National Cancer Institute.

5.  Preventive Surgery Can Reduce Cancer Risk in Women with BRCA Gene Mutations 7
(Posted: 05/28/2002, Updated: 10/04/2006) - Two separate studies in the May 23, 2002, issue of the New England Journal of Medicine support the practice of recommending preventive surgery in women with a genetic mutation that puts them at high risk of developing breast and gynecologic cancers.
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Table of Links

1http://www.cancer.gov/cancertopics/types/ovarian
2http://www.cancer.gov/clinicaltrials/search
3http://www.cancer.gov/clinicaltrials/results/BRCA0209
4http://www.cancer.gov/clinicaltrials/results/ovarian-ultrasound0208
5http://www.cancer.gov/clinicaltrials/results/IPchemo-QoL0207
6http://www.cancer.gov/clinicaltrials/results/ovarian-meta-analysis1206
7http://www.cancer.gov/clinicaltrials/results/preventive-surgery0502
8http://www.cancer.gov/clinicaltrials/results/ovarian?keyword=any+ovarian&page=2
9http://www.cancer.gov/clinicaltrials/results/ovarian?keyword=any+ovarian&page=3