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Call for Papers


Comparative Toxicogenomics Database (CTD)

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Environmental Health Perspectives Volume 111, Number 11, August 2003
Environmental Health Perspectives Toxicogenomics August 2003 Although the idea of drugs tailored precisely to individuals may seem like the stuff of science fiction, researchers in pharmacogenomics say it’s more like science future. The Focus
(p. A580) reviews the historical basis for pharmacogenomics and forecasts how this emerging discipline will change the face of medicine.

Purchase This Issue

  • Pharmacogenomics: Targeting Medicine’s Future
    A 580
  • Benzene’s Multiple Mechanisms of Toxicity
    A 590 & 1411
  • Arsenic, Inflammation, & Atherosclerosis
    1429

image credit: Photodisc, PharmGKB, Joseph Tart/EHP

Perspectives

Editorials

  • The Reality of Pharmacogenomics: Optimizing Therapeutic
    Decision Making-Craig R. Lee and Darryl C. Zeldin
    p. A 566 [HTML] [ Download PDF]

Environews

Forum

  • Fingerprinting Cancer Development . . . The EGP at Five Years . . . Genes and Environment: A SNPshot . . . A Big Circuit Model
    p. A 572
  • TXGnet: The Pharmacogenetics Research Network and the Pharmacogenetics and Pharmacogenomics Knowledge Base

    [HTML] [ Download PDF]

NCT Update
  • Toxicoproteomics: A Parallel Approach to Identifying Biomarkers
    p. A 578

    [HTML] [ Download PDF]

Focus
    Pharmacogenomics: The Promise of Personalized Medicine
    p. A 580

    [HTML] [ Download PDF]

Science Selections

  • Benzene’s Adverse Effects . . . Effect of SNPs on OPs
    p. A 590

    [HTML] [Download PDF]

Toxicogenomics

Articles

    Increased Influence of Genetic Variation on PON1 Activity in Neonates
    Jia Chen, Madhu Kumar, Wendy Chan, Gertrud Berkowitz, and James G. Wetmur
    [HTML] [ Download PDF]

    Mechanisms of Benzene-Induced Hematotoxicity and Leukemogenicity:
    cDNA Microarray Analyses Using Mouse Bone Marrow Tissue
    Byung-IL Yoon, Guang-Xun Li, Kunio Kitada, Yasushi Kawasaki, Katsuhide Igarashi, Yukio Kodama, Tomoaki Inoue, Kazuko Kobayashi, Jun Kanno, Dae-Yong Kim, Tohru Inoue, and Yoko Hirabayashi
    [HTML] [ Download PDF]

    Genetic Variation in Genes Associated with Arsenic Metabolism: Glutathione S-Transferase Omega 1-1 and Purine Nucleoside Phosphorylase Polymorphisms in European and Indigenous Americans
    Lizhi Yu, Kelly Kalla, Erin Guthrie, Amy Vidrine, and Walter T. Klimecki
    [HTML] [ Download PDF]

    Gene Expression of Inflammatory Molecules in Circulating Lymphocytes
    from Arsenic-Exposed Human Subjects
    Meei-Maan Wu, Hung-Yi Chiou, I-Ching Ho, Chien-Jen Chen, and Te-Chang Lee
    [HTML] [ Download PDF]

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