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Review Criteria for the Overall Application

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Multiproject applications have special review criteria in addition to the five standard NIH review criteria.

The overall application has the following special review criteria in addition to the five standard NIH review criteria:

  • Does the application adequately explain the following:
    • Scientific merit of each research project and core? The program as a whole?
    • Significance of the overall program goals?
    • Scientific gains and synergy achieved by combining the component projects into a multiproject program beyond the gains achievable if each project were pursued independently?
  • How well does the overall program incorporate innovative concepts and approaches?
  • Is the program cohesive? Do research projects and cores fit into a common theme?
  • Does the PI have sufficient time, effort, leadership ability, and scientific talent to develop a program of integrated research projects with a well-defined central research focus?
  • Are the key personnel qualified, trained, and committed? Do they add to the merit of the project? Can they devote adequate time and effort to the project?
  • Does the institution provide sufficient laboratory space, equipment, and other resources to support the project?
  • For renewal applications, do the program's accomplishments justify new funding?

Administrative considerations

  • Is the administrative and organizational structure sound?
  • Do the facilittes support the program objectives?

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