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Human Genome Project Information


Chromosome Mapping


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The Human Genome Project was completed in 2003. One of the key research areas was Chromosome Mapping. This page details that research.

Mapping is the construction of a series of chromosome descriptions that depict the position and spacing of unique, identifiable biochemical landmarks, including some genes, that occur on the DNA of chromosomes.

In 1990, DOE initiated projects to enrich the developing chromosome maps with markers for genes. In 1993 this effort led to the establishment of the Integrated Molecular Analysis of Gene Expression (I.M.A.G.E.) Consortium. I.M.A.G.E. members develop and array cDNA clones (representing the gene coding regions of the genome) and make them available worldwide.

Area HGP Goal Standard Achieved Date Achieved
Genetic Map 2- to 5-cM resolution map (600 – 1,500 markers) 1-cM resolution map (3,000 markers) September 1994
Physical Map 30,000 STSs 52,000 STSs October 1998
Gene Identification Full-length human cDNAs 15,000 full-length human cDNAs March 2003

For a more detailed explanation of mapping, see the U.S. DOE Primer on Molecular Genetics.

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Last modified: Friday, September 19, 2008

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