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Resources about laboratory animals used in biomedical research including legislation, publications, training, meetings, and organizations.

Cover of the Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
National Research Council.
Provides information that will enhance animal well-being, the quality of biomedical research, and the advancement of biologic knowledge that is relevant to humans or animals. A Spanish version is also available online.

Guía para el Cuidado y Uso de los Animales de Laboratorio
National Research Council. Institute of Laboratory Animal Resources.
Spanish version of the Guide for the Care and Use of Laboratory Animals.

Recognizing Pain in Animals
National Academies of Science. Institute for Laboratory Animal Research.
The National Academies have developed a free online resource to help those who care for and use laboratory animals, farm animals, and pets to prevent, recognize, and alleviate pain in different types of animals, from non-human primates to fish. The web site is related to a 2009 report on the Recognition and Alleviation of Pain in Laboratory Animals.

Animal Welfare Regulations
Government Printing Office.
Code of Federal Regulations, Title 9, Chapter 1, Subchapter A - Animal Welfare:

Part 1 Definition of Terms

Part 2 Regulations

Part 3 Standards

Part 4 Rules of Practice

Assessing the Health and Welfare of Laboratory Animals
University of Newcastle.
Tutorials and resources for guidance in recognizing signs of health and good welfare and identifying signs of pain, distress and poor welfare in laboratory animals.

Guidelines to Promote the Wellbeing of Animals Used for Scientific Purposes: The Assessment and Alleviation of Pain and Distress in Research Animals
Australian Government. National Health and Medical Research Council.
Published in 2008 to be used by investigators and members of insitutional ethics committees in Australia, this document is also relevant to people that conduct, review or manage research with animals all over the world.

Newcastle Consensus Meeting on Carbon Dioxide Euthanasia of Laboratory Animals, February 2006 (PDF|123KB)
In February 2006 a meeting was held at the University of Newcastle in the United Kingdom to bring together scientists who have examined CO2 as a euthanasia agent.

Animal Ethics InfoLink
This Australian Web site provides links to information for researchers, teachers and members of Animal Ethics Committees (similar to IACUCs) about accreditation and licensing, the 3Rs, and education and training as well as guidelines on a range of issues including animal care, animal supply, and procedures such as blood collection and wildlife research.

Refinements in husbandry, care and common procedures for non-human primates (PDF|518 KB)
Laboratory Animals.
This 2009 report provides guidance on the husbandry and care of non-human primates and on minimizing the adverse effects of some common procedures.

Resources Today for the Research of Tomorrow
USDA. NAL. Animal Welfare Information Center.
Watch this short video to learn more about the Animal Welfare Information Center (AWIC). The video is 12 minutes long and was produced in 1989.

The Ethics of Research Involving Animals
Nuffield Council on Bioethics.
This report is available in full and as a summary on the site. The working group raised moral and ethical questions regarding the use of animals in research.

Animal Welfare Policy Statements
American Veterinary Medical Association.
Position statements covering recommendations on antimicrobial use, euthanasia, abuse, pain, and other important animal welfare concerns.

Canadian Council on Animal Care (CCAC) Guidelines
Canadian Council on Animal Care.
Includes guidelines for animals used in research. Topics covered include transgenic animals, fish, wildlife, antibody production, laboratory animal facilties, appropriate endpoints, animal use protocol review and animal user training. Additional guidelines are developed in response to current and emerging needs of the research community and advances in laboratory animal care. Also see their Guide to the Care and Use of Experimental Animals, Vol. 1, 1993.

Methods and Welfare Considerations in Behavioral Research with Animals, 2002
DHHS. National Institutes of Health.
This handbook is intended to assist the Institutional Animal Care and Use Committee (IACUC) in the evaluation of protocols that employ various means to manipulate the behavior and health of laboratory animals.

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Last Modified: May 28, 2009


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			Institutional Animal Care and Use Committees


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			Disaster Planning


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			Environmental Enrichment and Exercise


			Import/Export


			Software and Technology


			Related Journals


			Organizations


			National Institutes of Health, Office of Laboratory Animal Welfare


			U.S. Food and Drug Adminstration, Center for Drug Evaluation and Research


			Reporting a Violation


			USDA Licensing and Registration Forms


			USDA Inspection Reports


			Veterinary Medicine Libraries

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