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Oral Contraceptives Falter due to Obesity ![]() A study out of Oregon finds that obesity can curtail the effectiveness of contraceptives. Although the oral contraceptives worked for normal-weight and obese women, the drug took longer to achieve drug concentration levels to prevent pregnancy. |
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Using Baking Soda to Improve Health ![]() A study of 134 patients found that a small dose of sodium bicarbonate (baking soda) helped slow down the decline of kidney function in patients who also underwent regular treatment for kidney failure. |
IL-2 Immunotherapy Fails to Benefit HIV-Infected Individuals Already Taking Antiretrovirals
The third phase of clinical trials for an immune therapy booster individuals with HIV can use to increase their T cell count, has done little to combat diseases that can lead to death. |
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Anti-HIV Gel Shows Promise in Large-scale Study in Women
A 3,000-women study tested the effectiveness of anti-HIV gels that would be inserted into the vagina to deter virus transmission during intercourse. |
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Age is not a key factor in cancer survival, but clinical trials exclude older patients ![]() In the November Independent Journal of Clinical Practice one article notes that 60 percent of people battling cancer are older than 60, however this group is not reflected in clinical trials. |
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Testing Vitamins in Hearing Loss Prevention ![]() Researchers at the University of Michigan are testing whether vitamins and minerals can be used to reverse noise-induced hearing loss. While testing a vitamin-mineral cocktail on guinea pigs, researchers found that 80 percent of hearing loss was prevented. Four clinical trails are being conducted around the world. |
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What Went Wrong ![]() A study in the Nov. 3 online issue of the Journal of Experimental Medicine details what happened in the second phase of the clinical trial for the HIV-1 vaccine in September 2007. The drug seemed to hold promise, but was found to increase the risk of contracting the virus. |
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The Basics of Clinical Trials ![]() Physicians and scientists at the University of Cincinnati are working to make sure Americans know the truth about clinical trials, who participates and the possible benefits. |
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NIH Site Reveals Info on Clinical Trials and Minors
The new Web site from NIH uses videos to discuss the reasoning behind involving children in clinical trials and what trials are being conducted across the nation. The site is aimed at parents and health care providers and explains the different methods of research and what can be expected if a child participates in a clinical trial. |
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Multi-strain influenza vaccine passes first phase of clinical trials ![]() Researchers from the University of Texas at Galveston are gearing up to present their findings in October at the Conference on Agents and Chemotherapy and the Infectious Disease Society of America. Their work, underwritten by a grant from the Bill and Melinda Gates Foundation, has led to a multi-strain influenza vaccine that has passed the first phase of clinical trials. |
The Minority Role in Clinical Trials
When it comes to creating an accurate picture of what it takes to cure diseases and develop vaccines, a few pieces of the puzzle are missing. |