David W Hoyt, Ph.D.
Scientific Facility Lead and Senior Research Scientist II, WR Wiley Environmental Molecular Sciences Laboratory, High Field NMR Facility3335 Q Avenue, P.O. Box 999, K8-98
Richland,
WA
99352
USA
Current Activities and Projects
- Managing the High Field NMR User Facility which includes 12 NMR's (900 MHz to 300 MHz) and One pulsed FT-EPR
- Accessing laboratory equipment via remote collaboration tools - EMSL's Virtual NMR Facility
- Collaborating on several biomolecular NMR projects:
Structure investigations of a large tumor supressor protein BRCA1 complexed to partner proteins using modern multi-dimensional heteronuclear NMR methods
Structural analysis of amyloid fibril formation in detergents
Structure determination studies of Apolipoproteins
Research Interests
- Nuclear Magnetic Resonance Spectroscopy
- Structural Basis for Protein-Protein Interactions
- Receptor - Growth Factor Recognition in Signaling
- Structural Basis for Protein-Lipid Interactions
- Protein Transport Across Membranes
- Metabolomics
- Other Spectroscoples - CD, Fluorescence.
Education
1990 Ph.D., Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas
1987 M.A., Biochemistry, University of Delaware, Newark, Delaware
1983 B.S., Chemistry, Millersville University, Millersville, Pennsylvania
Awards, Honors, & Appointments
2007 US Patent Submission 15387E - Discrete Magic Angle Turning (DMAT) Probe
