B's, Ts, Tolls and DCs in Systemic Autoimmunity |
|
|---|---|
|
|
|
| Launch in standalone player | |
| Air date: | Wednesday, June 03, 2009, 4:15:00 PM Time displayed is Eastern Time, Washington DC Local |
| Category: | Immunology |
| Description: | Mark Shlomchik is an outstanding B cell expert with a primary focus on autoimmunity. Mark was first in reporting an antibody-independent role of B cells in autoimmune disease. Stemming from his in-depth analysis of an anti-rheumatoid factor transgenic mouse model, he described the prevalence of somatic hypermutated antibody responses in the absence of germinal centers. He has studied the various stages of B cell development, including the germinal center reaction, plasma cells and memory B cells using a variety of approaches: flow cytometry and expression analysis of specific populations, analysis of antibody sequences and cell imaging. Most recently, he has found divergent roles for TLR9 and TLR7 in the lupus autoimmune disease, and has reported on the use of B cell depletion therapy in treatment for diabetes. Come to hear his talk and give the B cells some love!
For more information, visit The Immunology Interest Group |
| Author: | Mark Shlomchik, Professor of Laboratory Medicine & Immunobiology, Yale University School of Medicine |
| Runtime: | 75 minutes |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 15149 |
| CIT Live ID: | 7462 |
| Permanent link: | http://videocast.nih.gov/launch.asp?15149 |