Pathways of Memory CD8 T Cell Development During Infection

 


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Air date: Wednesday, May 20, 2009, 4:15:00 PM
Time displayed is Eastern Time, Washington DC Local
Category: Immunology
Description: Susan Kaech will be visiting NIH on May 20th as our speaker for the IIG seminar series. As most of you probably know, Sue has been at the forefront of characterizing the CD8+ T cell response to viral infections both as a post-doc in Rafi Ahmed's lab and since starting her own group at Yale in 2004. She has recently focused on finding ways of discriminating short-lived effector T cells from the precursors of long-lasting memory T cells in response to model pathogens. Sue is an engaging speaker and this should be a great seminar.

Recent publications from her lab include these:
Expression of IL-7R alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection http://www.pnas.org/content/104/28/11730.full
Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor http://www.cell.com/immunity/retrieve/pii/S1074761307003718

For more information, visit
The Immunology Interest Group
Author: Dr. Susan Kaech, Associate Professor, Department of Immunobiology, Yale University
Runtime: 75 minutes
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CIT File ID: 15110
CIT Live ID: 7460
Permanent link: http://videocast.nih.gov/launch.asp?15110