Proton beam therapy for prostate cancer: I have studied the subject matter thoroughly. As a scientist, I have access to the primary medical literature, and I have carefully scrutinized over 100 publications on the subject. I have also had discussions with over 20 men who had so-called conventional treatments (radical prostatectomy, various forms of external beam radiation, and two forms of brachytherapy), in addition to 30 men who had proton therapy. My conclusions are that, indeed, as argued by several contributors to this compilation, all forms of treatment are equally successful. The difference lies in the side effects, particularly posttreatment.
My particular concerns with respect to treatment are the minimization of the chances for urinary (i.e. incontinence) and sexual (i.e. erectile dysfunction) complications. My research shows that proton radiation offers a much better chance of avoiding such complications than conventional treatment. Some adverse medical literature notwithstanding, there are numerous reports in primary publications, most significant among them those by doctors/researchers without a vested interest in any of the forms of therapy, which point to the superior aspects of proton radiation in these respects. These papers show that it has become a standard alternative to other methods, that quality of life issues have become paramount for men afflicted with prostate cancer, and that the choice of treatment should be left to the patient.
The statement that there are no rigorous studies the compare modern conventional IMRT with proton radiation therapy is correct. What is incorrect, indeed disingenuous, is to construe this as an argument against proton radiation as a treatment choice. There are no studies that show that conventional treatment is better or even equal to protons. However, there is unequivocal science. Nobody can argue with the existence of the Bragg peak and therefore the corresponding reduction in exposure of nontarget tissue.
I therefore would have to vehemently disagree with the proposal to stop Medicare reimbursements for proton therapy in the treatment of prostate cancer.
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