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Animal Pharmacology and Toxicology

This service can be used to provide pharmacokinetic and safety assessments of products in mice, rats, rabbits, dogs, and nonhuman primates.

They following types of studies can be conducted:

  • Quantitation of drug and metabolite levels in plasma.
  • Determination of bioavailability and other pharmacokinetic parameters.
  • Evaluation of products as substrates, inhibitors, or inducers of cytochrome P450 enzymes.
  • In vitro genetic toxicity assessments (e.g., Ames test).
  • Determination of maximum tolerated dose.
  • Determination of systemic and specific target-organ toxicity following single or multiple administrations of product.
  • Studies can be conducted under GLP guidelines.

The current contractor for this service is SRI International, Menlo Park CA.

NIAID’s point of contact for this service is Dr. Hao Zhang.

Contact Info

NIAID’s point of contact for this service is Dr. Hao Zhang.

Requesting Access to NIAID Contract Services




 

Contact Info

NIAID’s point of contact for this service is Dr. Hao Zhang.

Requesting Access to NIAID Contract Services