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Evidence-Based Medicine

Closing the Quality Gap: Antibiotic Prescribing Behavior. Agency for Healthcare Research and Quality, Technical Review 9, January 2006, 158 pp. The fourth publication in this multi-volume series provides a critical analysis of quality improvement strategies to reduce inappropriate antibiotic prescribing, targeting both prescribing of antibiotics for non-bacterial illnesses and prescribing of broad-spectrum antibiotics when narrow-spectrum agents are indicated. (AHRQ 04(06)-0051-4)

Closing the Quality Gap: Asthma Care Strategies. Agency for Healthcare Research and Quality, Technical Review 9, January 2007, 199 pp. The fifth publication in this multi-volume series presents an evaluation of the evidence that quality improvement strategies can improve the processes and outcomes of outpatient care for children and adults with asthma. (AHRQ 04(07)-0051-5)

Closing the Quality Gap: Care Coordination. Agency for Healthcare Research and Quality, Technical Review 9, June 2007, 158 pp. The seventh publication in this multi-volume series defines care coordination interventions and discusses how they are influenced by factors in the health care setting and how they relate to patient outcomes and health care costs. (AHRQ 04(07)-0051-7)

Closing the Quality Gap: Prevention of Healthcare-Associated Infections. Agency for Healthcare Research and Quality, Technical Review 9, January 2007, 107 pp. The sixth publication in this multi-volume series examines the effects of quality improvement strategies on promoting adherence to interventions for prevention of selected infections (surgical site infections, central-line associated bloodstream infections, ventilator-associated pneumonia, and catheter-associated urinary tract infections) and on the rates of such infections. (AHRQ 04(07)-0051-6)

Consumer-Oriented Strategies for Improving Health Benefit Design: An Overview. Agency for Healthcare Research and Quality, Technical Review 15, July 2007, 47 pp. Discusses the likely effects of consumer-directed health plans, tiered networks, and expanded quality data collection and dissemination on the use and costs of health care. (AHRQ 07-0067)

Criteria for Distinguishing Effectiveness from Efficacy Trials in Systematic Reviews. Agency for Healthcare Research and Quality, Technical Review 12, April 2006, 19 pp. Proposes and tests seven hallmarks of study design to create a tool that can help researchers and those producing systematic reviews to distinguish more readily and more consistently between efficacy and effectiveness studies. (AHRQ 06-0046)

A Critical Analysis of Care Coordination Strategies for Children with Special Health Care Needs. Agency for Healthcare Research and Quality, Technical Review 14, June 2007, 35 pp. Examines the issue of care coordination for children with special health care needs, particularly those aspects of care coordination that are especially important to current practice and policy challenges. (AHRQ 07-0054)

Developing a Methodology for Establishing a Statement of Work for a Policy-Relevant Technical Analysis. Agency for Healthcare Research and Quality, Technical Review 11, January 2006, 35 pp. Describes a project initiated by the Duke Evidence-based Practice Center to contribute to the improvement of the evidence-base practice process, focusing on specific actions that could serve to improve process efficiency and stakeholder satisfaction. (AHRQ 06-0026)

Empirical Evaluation of the Association Between Methodological Shortcomings and Estimates of Adverse Events. Agency for Healthcare Research and Quality, Technical Review 13, October 2006, 31 pp. Assesses the association between perceived methodological shortcomings and estimates of serious complications from surgical and medical interventions. Compares estimates of harms from studies meeting eight pre-defined criteria designed to assess the quality of harms reporting to studies not meeting the criteria. (AHRQ 07-0003)

Evidence-Based Practice: AHRQ's Role in Generating and Disseminating Knowledge. M. Coopey, M. Nix, C. Clancy, AORN Journal 86(5): November 2007, 857-860. Describes three of AHRQ's initiatives for promoting evidence-based practice—the Evidence-based Practice Centers program, the National Guideline Clearinghouse, and the National Quality Measures Clearinghouse—and discusses the role and contributions of nurses and nursing research in furthering evidence-based practice. (AHRQ 08-R023)

The Risk of Aprotinin: A Conflict of Evidence. A. Sedrakyan, D. Atkins, T. Treasure, Lancet 367: April 29, 2006, 1376-1377. Discusses the difference between evidence from the randomized trials and a multivariable-adjusted cohort study of use of aprotinin in high-risk patients. (AHRQ 06-R066)

Strategies to Support Quality-Based Purchasing: A Review of the Evidence. Agency for Healthcare Research and Quality, Technical Review 10, July 2004, 73 pp. Develops a conceptual model of how incentives influence provider behavior, summarizes what is known from randomized controlled trials about the effectiveness of different quality-based purchasing strategies, describes ongoing research, and presents results of simulations to determine whether outcomes reports are too influenced by chance events to be used in making quality-based purchasing decisions. (AHRQ 04-0057)
Summary. July 2004 (AHRQ 04-P024)

Translating Research Into Evidence-Based Nursing Practice and Evaluating Effectiveness. M. Coopey, M. Nix, C. Clancy, Journal of Nursing Care Quality 21(3): July-September 2006, 195-202. Provides an overview of nursing-relevant components of AHRQ's efforts to improve patient care through translating research into evidence-based nursing practice and evaluating the effectiveness of the implementation in terms of patient outcomes and safety. (AHRQ 06-R061)

Updating Systematic Reviews. Agency for Healthcare Research and Quality, Technical Review 16, September 2007, 71 pp. Discusses the extent to which systematic reviews require updating and the signals that indicate the need to update a systematic review, particularly a review that is directly relevant to clinical practice. (AHRQ 07-0087)

Will It Work Here? A Decisionmakers Guide to Adopting Innovations. Agency for Healthcare Research and Quality, September 2008, 116 pp. Helps decisionmakers determine whether an innovation would be a good fit for their health care organizations. (AHRQ 08-0051)

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Evidence Reports/Technology Assessments

Cancer and Blood Disorders

Adnexal Mass, Management.
Evidence Report/Technology Assessment, No. 130.
Evidence Report. January 2006 (AHRQ 06-E004)

Breast Cancer Care in Women, Measuring Quality.
Evidence Report/Technology Assessment, No. 105.
Summary. September 2004 (AHRQ 04-E030-1)
Evidence Report. October 2004 (AHRQ 04-E030-2)

Cancer Care Quality Measures, Colorectal Cancer.
Evidence Report/Technology Assessment, No. 138.
Evidence Report. May 2006 (AHRQ 06-E002)

Cancer Care Quality Measures, Symptoms and End-of-Life.
Evidence Report/Technology Assessment, No. 137.
Evidence Report. May 2006 (AHRQ 06-E001)

Cancer Clinical Trials, Recruitment of Underrepresented Populations.
Evidence Report/Technology Assessment No. 122.
Summary. June 2005 (AHRQ 05-E019-1)
Evidence Report. June 2005 (AHRQ 05-E019-2)

Cancer Control Interventions, Diffusion and Dissemination.
Evidence Report/Technology Assessment, No. 79.
Summary. May 2003 (AHRQ 03-E032)
Evidence Report. May 2003 (AHRQ 03-E033)

Collection and Use of Cancer Family History in Primary Care.
Evidence Report/Technology Assessment, No. 159.
Evidence Report. October 2007 (AHRQ 08-E001)

Hereditary Nonpolyposis Colorectal Cancer: Diagnostic Strategies and Their Implications.
Evidence Report/Technology Assessment, No. 150.
Evidence Report. May 2007 (AHRQ 07-E008)

Hydroxyurea Treatment of Sickle Cell Disease.
Evidence Report/Technology Assessment, No. 165.
Evidence Report. February 2008 (AHRQ 08-E007)

Impact of Gene Expression Profiling Tests on Breast Cancer Outcomes.
Evidence Report/Technology Assessment No. 160.
Evidence Report. January 2008 (AHRQ 08-E002)

Ovarian Cancer, Genomic Tests for Detection and Management.
Evidence Reports/Technology Assessment, No. 145.
Evidence Report. October 2006 (AHRQ 07-E001)

Small Cell Lung Cancer, Management.
Evidence Report/Technology Assessment, No. 143.
Evidence Report. July 2006 (AHRQ 06-E016)

Complementary and Alternative Care

Meditation Practices for Health.
Evidence Report/Technology Assessment, No. 155.
Evidence Report. June 2007 (AHRQ 07-E010)

Dietary Supplements

B Vitamins and Berries and Age-Related Neurodegenerative Disorders.
Evidence Report/Technology Assessment No. 134.
Evidence Report. April 2006 (AHRQ 06-E008)

Effectiveness and Safety of Vitamin D in Relation to Bone Health.
Evidence Report/Technology Assessment No. 158.
Evidence Report. (AHRQ 07-E013)

Multivitamin/Mineral Supplements, Chronic Disease Prevention.
Evidence Report/Technology Assessment, No. 139.
Evidence Report. May 2006 (AHRQ 06-E012)

Omega-3 Fatty Acids, Effects in Type II Diabetes, Rheumatoid Arthritis, and Other Diseases.
Evidence Report/Technology Assessment, No. 89.
Summary. March 2004 (AHRQ 04-E012-1)
Evidence Report. March 2004 (AHRQ 04-E012-2)

Omega-3 Fatty Acids, Effects on Arrhythmogenic Mechanisms in Culture Studies.
Evidence Report/Technology Assessment No. 92.
Summary. March 2004 (AHRQ 04-E011-1)
Evidence Report. March 2004 (AHRQ 04-E011-2)

Omega-3 Fatty Acids, Effects on Asthma.
Evidence Report/Technology Assessment, No. 91.
Summary. March 2004 (AHRQ 04-E013-1)
Evidence Report. March 2004 (AHRQ 04-E013-2)

Omega-3 Fatty Acids, Effects on Cancer.
Evidence Report/Technology Assessment, No. 113.
Summary. February 2005 (AHRQ 05-E010-1)
Evidence Report. February 2005 (AHRQ 05-E010-2)

Omega-3 Fatty Acids, Effects on Cardiovascular Disease.
Evidence Report/Technology Assessment, No. 94.
Summary. March 2004 (AHRQ 04-E009-1)
Evidence Report. March 2004 (AHRQ 04-E009-2)

Omega-3 Fatty Acids, Effects on Cardiovascular Risk Factors.
Evidence Report/Technology Assessment, No. 93.
Summary. March 2004 (AHRQ 04-E010-1)
Evidence Report. March 2004 (AHRQ 04-E010-2)

Omega-3 Fatty Acids, Effects on Child and Maternal Health.
Evidence Report/Technology Assessment, No. 118.
Summary. August 2005 (AHRQ 05-E025-1)
Evidence Report. August 2005 (AHRQ 05-E025-2)

Omega-3 Fatty Acids, Effects on Cognitive Functions.
Evidence Report/Technology Assessment, No. 114.
Summary. February 2005 (AHRQ 05-E011-1)
Evidence Report. February 2005 (AHRQ 05-E011-2)

Omega-3 Fatty Acids, Effects on Eye Health.
Evidence Report/Technology Assessment, No. 117.
Summary. July 2005 (AHRQ 05-E008-1)
Evidence Report. February 2005 (AHRQ 05-E008-2)

Omega-3 Fatty Acids, Effects on Mental Health.
Evidence Report/Technology Assessment, No. 116.
Summary. July 2005 (AHRQ 05-E022-1)
Evidence Report. July 2005 (AHRQ 05-E022-2)

Omega-3 Fatty Acids, Effects on Organ Transplantation.
Evidence Report/Technology Assessment, No. 115.
Summary. February 2005 (AHRQ 05-E012-1)
Evidence Report. February 2005 (AHRQ 05-E012-2)

Soy, Effects on Health Outcomes.
Evidence Report/Technology Assessment, No. 126.
Summary. July 2005 (AHRQ 05-E024-1)
Evidence Report. July 2005 (AHRQ 05-E024-2)

Ear, Nose, and Throat Conditions

Sinusitus, Acute Bacterial—Update.
Evidence Report/Technology Assessment No. 124.
Summary. June 2005 (AHRQ 05-E020-1)
Evidence Report. June 2005 (AHRQ 05-E020-2)

Heart and Vascular Diseases

Abdominal Aortic Aneurysm, Endovascular and Open Surgical Repairs.
Evidence Report/Technology Assessment No. 144.
Evidence Report. August 2006 (AHRQ 06-E017)

Carbohydrate and Lipid Disorders and Relevant Considerations in Persons with Spinal Cord Injury.
Evidence Report/Technology Assessment, No. 163.
Evidence Report. January 2008 (AHRQ 08-E005)

Cardiac Resynchronization Therapy and Implantable Defibrillators in Left Ventricular Systolic Dysfunction.
Evidence Report/Technology Assessment, No. 152.
Evidence Report. June 2007 (AHRQ 07-E009)

Heart Failure, Cardiac Resynchronization Therapy.
Evidence Report/Technology Assessment, No. 106.
Summary. November 2004 (AHRQ 05-E001-1)
Evidence Report. November 2004 (AHRQ 05-E001-2)

Heart Failure Diagnosis and Prognosis, Testing for BNP and NT-proBNP.
Evidence Report/Technology Assessment No. 142.
Evidence Report. September 2006 (AHRQ 06-E014)

Post-Myocardial Infarction Depression.
Evidence Report/Technology Assessment, No. 123.
Summary. May 2005 (AHRQ 05-E018-1)
Evidence Report. May 2005 (AHRQ 05-E018-2)

Infectious Diseases

Antiretroviral Drug Resistance in the Developing World.
Evidence Report/Technology Assessment, No. 156.
Evidence Report. July 2007 (AHRQ 07-E014)

Information Technology

Health Information Technology, Costs and Benefits.
Evidence Report/Technology Assessment, No. 132.
Evidence Report. April 2006 (AHRQ 06-E006)

Telemedicine for the Medicare Population—Update.
Evidence Report/Technology Assessment No. 131.
Evidence Report. February 2006 (AHRQ 06-E007)

Kidney Conditions

Prevention of Fecal and Urinary Incontinence in Adults.
Evidence Report/Technology Assessment, No. 161.
Evidence Report. December 2007 (AHRQ 08-E003)

Utility of Monitoring Mycophenolic Acid in Solid Organ Transplant Patients.
Evidence Report/Technology Assessment No. 164.
Evidence Report. February 2008 (AHRQ 08-E006)

Lung Conditions

Asthma, Work-Related, Diagnosis and Management.
Evidence Report/Technology Assessment, No. 129.
Summary. October 2005 (AHRQ 06-E003-1)
Evidence Report. November 2005 (AHRQ 06-E003-2)

Chronic Obstructive Pulmonary Disease, Spirometry.
Evidence Report/Technology Assessment, No. 121.
Summary. August 2005 (AHRQ 05-E017-1)
Evidence Report. September 2005 (AHRQ 05-E017-2)

Mental Health Conditions and Substance Abuse

Depression, CYP450 Testing for Adults Treated with SSRIs.
Evidence Report/Technology Assessment, No. 146.
Evidence Report. January 2007 (AHRQ 07-E002)

Eating Disorders, Management.
Evidence Report/Technology Assessment, No. 135.
Evidence Report. April 2006 (AHRQ 06-E010)

Tobacco Use, Prevention, Cessation, and Control.
Evidence Report/Technology Assessment, No. 140.
Evidence Report. June 2006 (AHRQ 06-E015)

Metabolic, Nutritional, and Endocrine Conditions

Diabetes Education for Children with Type 1 Diabetes Mellitus and Their Families.
Evidence Report/Technology Assessment No. 166.
Evidence Report. April 2008 (AHRQ 08-E011)

Diabetes Mellitus, Islet Transplantation in Patients.
Evidence Report/Technology Assessment, No. 98.
Summary. July 2004 (AHRQ 04-E017-1)
Evidence Report. August 2004 (AHRQ 04-E017-2)

Diabetes Mellitus, Use of Glycated Hemoglobin and Microalbuminuria.
Evidence Report/Technology Assessment No. 84.
Summary. July 2003 (AHRQ 03-E048)
Evidence Report. October 2003 (AHRQ 04-E001)

Effectiveness of Weight Management Programs in Children and Adolescents.
Evidence Report/Technology Assessment No. 170.
Evidence Report. September 2008. (AHRQ 08-E014)

Impaired Glucose Tolerance and Fasting Glucose, Diagnosis, Prognosis, and Therapy.
Evidence Report/Technology Assessment, No. 128.
Summary. August 2005 (AHRQ 05-E026-1)
Evidence Report. September 2005 (AHRQ 05-E026-2)

Obesity, Pharmacological and Surgical Treatment.
Evidence Report/Technology Assessment, No. 103.
Summary. July 2004 (AHRQ 04-E028-1)
Evidence Report. July 2004 (AHRQ 04-E028-2)

Methodology

Community-Based Participatory Research.
Evidence Report/Technology Assessment, No. 99.
Summary. August 2004 (AHRQ 04-E022-1)
Evidence Report. July 2004 (AHRQ 04-E022-2)

Musculoskeletal Disorders

Chronic Fatigue Syndrome, Defining and Managing.
Evidence Report/Technology Assessment, No. 42.
Summary. May 2004 (AHRQ 01-E061)
Evidence Report. May 2004 (AHRQ 02-E001)

Disability and Chronic Fatigue Syndrome, Systematic Literature Review.
Evidence Report/Technology Assessment No. 66.
Summary. December 2002 (AHRQ 03-E006)
Evidence Report. December 2002 (AHRQ 03-E007)

Treatment of Primary and Secondary Osteoarthritis of the Knee.
Evidence Report/Technology Assessment No. 157.
Evidence Report. July 2007 (AHRQ 07-E012)

Nerve and Brain Conditions

Dementia, Pharmacological Treatment.
Evidence Report/Technology Assessment, No. 97.
Summary. April 2004 (AHRQ 04-E018-1)
Evidence Report. April 2004 (AHRQ 04-E018-2)

Insomnia, Manifestations and Management.
Evidence Report/Technology Assessment, No. 125.
Summary. June 2005 (AHRQ 05-E021-1)
Evidence Report. June 2005 (AHRQ 05-E021-2)

Parkinson's Disease, Diagnosis and Treatment.
Evidence Report/Technology Assessment No. 57.
Summary. May 2003 (AHRQ 03-E039)
Evidence Report. May 2003 (AHRQ 03-E040)

Spinal Cord Injury, Sexuality and Reproductive Health.
Evidence Report/Technology Assessment, No. 109.
Summary. December 2004 (AHRQ 05-E003-1)
Evidence Report. November 2004 (AHRQ 05-E003-2)

Stroke, Evaluation and Treatment.
Evidence Report/Technology Assessment, No. 127.
Summary. July 2005 (AHRQ 05-E023-1)
Evidence Report. July 2005 (AHRQ 05-E023-2)

Obstetric and Gynecologic Conditions

Bariatric Surgery in Women of Reproductive Age: Special Concerns for Pregnancy.
Evidence Report/Technology Assessment No. 169.
Evidence Report. September 2008 (AHRQ 08-E013)

Breastfeeding and Maternal and Infant Health Outcomes in Developed Countries.
Evidence Report/Technology Assessment No. 153.
Evidence Report. April 2007 (AHRQ 07-E007)

Cesarean Delivery on Maternal Request.
Evidence Report/Technology Assessment, No. 133.
Evidence Report. March 2006 (AHRQ 06-E009)

Effectiveness of Assisted Reproductive Technology.
Evidence Report/Technology Assessment No. 167.
Evidence Report. May 2008 (AHRQ 08-E012)

Episiotomy Use in Obstetrical Care.
Evidence Report/Technology Assessment, No. 112.
Summary. May 2005 (AHRQ 05-E009-1)
Evidence Report. May 2005 (AHRQ 05-E009-2)

Management of Uterine Fibroids: An Update of the Evidence.
Evidence Report/Technology Assessment, No. 154.
Evidence Report. July 2007 (AHRQ 07-E011).

Menopause-Related Symptoms, Management.
Evidence Report/Technology Assessment, No. 120.
Summary. March 2005 (AHRQ 05-E016-1)
Evidence Report. March 2005 (AHRQ 05-E016-2)

Outcomes of Maternal Weight Gain.
Evidence Report/Technology Assessment No. 120.
Evidence Report. May 2008 (AHRQ 08-E009)

Perinatal Depression, Prevalence and Screening.
Evidence Report/Technology Assessment, No. 119.
Summary. February 2005 (AHRQ 05-E006-1)
Evidence Report. February 2005 (AHRQ 05-E006-2)

Therapeutic Management, Delivery, and Postpartum Risk Assessment and Screening in Gestational Diabetes.
Evidence Report/Technology Assessment, No. 162.
Evidence Report. February 2008 (AHRQ 08-E004)

Oral and Gastrointestinal Disorders

Celiac Disease.
Evidence Report/Technology Assessment, No. 104.
Summary. June 2004 (AHRQ 04-E029-1)
Evidence Report. July 2004 (AHRQ 04-E029-2)

Periodontitis, Scaling and Root Planing Therapy.
Evidence Report/Technology Assessment, No. 88.
Summary. January 2004 (AHRQ 04-E014-1)
Evidence Report. Vols. 1 & 2, March 2004 (AHRQ 04-E014-2)

Pediatric Conditions

Toilet Training.
Evidence Report/Technology Assessment, No. 147.
Evidence Report. December 2006 (AHRQ 07-E003)

Public Health Emergency Preparedness

Bioterrorism Preparedness, Pediatric Anthrax.
Evidence Report/Technology Assessment, No. 141.
Evidence Report. July 2006 (AHRQ 06-E013)

Quality Improvement and Patient Safety

Effectiveness of Continuing Medical Education.
Evidence Report/Technology Assessment, No. 149.
Evidence Report. February 2007 (AHRQ 07-E006)

End-of-Life Care and Outcomes.
Evidence Report/Technology Assessment, No. 110.
Summary. December 2004 (AHRQ 05-E004-1)
Evidence Report. December 2004 (AHRQ 05-E004-2)

Literacy and Health Outcomes.
Evidence Report/Technology Assessment, No. 87.
Summary. January 2004 (AHRQ 04-E007-1)
Evidence Report. January 2004 (AHRQ 04-E007-2)

Minority Healthcare Quality, Improvement Strategies.
Evidence Report/Technology Assessment, No. 90.
Summary. January 2004 (AHRQ 04-E008-1)
Evidence Report. June 2003 (AHRQ 04-E008-2)

Nurse Staffing and Quality of Patient Care.
Evidence Report/Technology Assessment, No. 151.
Evidence Report. March 2007 (AHRQ 07-E005)

Patient Safety, Effects of Working Conditions.
Evidence Report/Technology Assessment, No. 74.
Summary. March 2003 (AHRQ 03-E024)
Evidence Report. May 2003 (AHRQ 03-E031)

Periodic Health Evaluation, Value.
Evidence Report/Technology Assessment, No. 136.
Evidence Report. April 2006 (AHRQ 06-E011)

Violence Prevention in Adolescents.
Evidence Report/Technology Assessment, No. 107.
Summary. September 2004 (AHRQ 04-E032-1)
Evidence Report. October 2004 (AHRQ 04-E032-2)

Skin Conditions

Heparin To Treat Burn Injury.
Evidence Report/Technology Assessment, No. 148.
Evidence Report. December 2006 (AHRQ 07-E004)

Wound Healing, Laser Treatment and Vacuum-Assisted Closure.
Evidence Report/Technology Assessment No. 111.
Summary. December 2004 (AHRQ 05-E005-1)
Evidence Report. December 2004 (AHRQ 05-E005-2)

A complete list of current Evidence Reports/Technology Assessments is available on the AHRQ Web site at http://www.ahrq.gov/clinic/epcix.htm.

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