Approval of extensions

• FAQ. May the IACUC administratively extend approval of a project that has expired?
• Lab Animal. 2007; 36(7). (PDF - 60 KB)
• Lab Animal. 2003; 32(9):33-36, question #8.

Approval methods

• FAQ. What are the possible methods of IACUC approval?
• Lab Animal. 2007; 36(9). (PDF - 77 KB)
• Lab Animal. 2003; 32(9):33-36, question #4.
• Lab Animal. 2002; 31(9):28-31.
• Contemporary Topics. 2001; 40(6):8.
• Lab Animal. 2001; 30(6):18-20.
• Lab Animal. 2001; 30(3):15.
• Lab Animal. 1998; 27(8):18.
• ILAR News. 1993; 35(3-4):47-49, question #3.

Collaborating institutions

• FAQ. When institutions collaborate or when the performance site is not the grantee institution, which IACUC is responsible for review of the research activity?
• Lab Animal. 2009; 38(6). (PDF - 188 KB)
• NIH Guide for Grants and Contracts. 2/12/2001, Notice: NOT-OD-01-017.

Conditional approvals

• FAQ. May the IACUC grant conditional or provisional approval?
• Lab Animal. 2008; 37(2). (PDF - 95 KB)
• Lab Animal. 2003; 32(9):33-36, question #2.
• OPRR Reports. 1990; 90-01, 5/21/1990.

DMR & FCR

• FAQ. May an IACUC use designated member review (DMR) to review an animal study protocol subsequent to full committee review (FCR) when modifications are needed to secure approval?
• NIH Guide for Grants and Contracts. 1/8/2009, Notice: NOT-OD-09-035.
• Lab Animal. 2002; 31(9):28-31.

Foreign-derived samples

• FAQ. Is IACUC approval required for the collection of samples in foreign countries from captive wild animals or research colonies?

Foreign institutions

• FAQ. If an animal activity will be performed outside of the US (either by a non-US grantee or by a foreign institution as a subproject for a domestic grantee), is the grantee’s IACUC required to review and approve that activity?
• Contemporary Topics. 1997; 36(2):47-50, question #2.

Frequency

• FAQ. How frequently should the IACUC review research protocols?
• Lab Animal. 2000; 29(3):18-19.
• ILAR News. 1993; 35(3-4):47-49, question #7.
• ILAR News. 1991; 33(4):68-70, question #8.

Grant review

• FAQ. Is the IACUC required to review the grant application?
• Lab Animal. 2006; 35(2):16-18.
• Lab Animal. 2003; 32(9):33-36, question #1.
• Lab Animal. 1999; 28(7):21.

Nonresearch activities

• FAQ. Is IACUC approval required for the use of animals in breeding programs, as blood donors, as sentinels in disease surveillance programs, or for other non-research purposes?

Nontraditional species

• FAQ. What guidelines should IACUCs follow for fishes, amphibians, reptiles, birds, and other nontraditional species used in research?
• Contemporary Topics. 1997; 36(2):47-50, question #6.

Pilot studies

• FAQ. May the IACUC approve pilot studies?
• Lab Animal. 2001; 30(3):21.

PIs

• FAQ. Is it acceptable to have different individuals named as PI on the grant application and the IACUC protocol?
• Lab Animal. 2007; 36(1). (PDF - 73 KB)

3 R’s

• FAQ. Should the IACUC consider the three “Rs” of alternatives when reviewing protocols?
• Lab Animal. 2008; 37(7) (PDF - 95 KB)

Review criteria

• FAQ. What criteria should the IACUC consider when reviewing protocols?

Scientific merit

• FAQ. Is the IACUC responsible for judging the scientific merit of proposals?
• ILAR News. 1991; 33(4):68-70, question #7.

Significant changes

• FAQ. What is considered a significant change to a project that would require IACUC review?
• Lab Animal. 2009; 38(2):45. (PDF - 112 KB)
• NIH Guide for Grants and Contracts. 6/6/2003, Notice: NOT-OD-03-046.
• Lab Animal. 1995; 24(9):24-26, question #1.
• Lab Animal. 2007; 36(7). (PDF - 60 KB)

SOPs

• FAQ. May standard operating procedures (SOPs) or blanket protocols that cover a number of procedures be utilized in lieu of repeating descriptions of identical procedures in multiple protocols?

Time of grant award

• FAQ. Does the IACUC have to review proposed animal research activities at the time of grant award if the animal research activities will not be conducted until year 4 or 5 of a grant?
• “Just-In-Time”. Federal Register, 8/7/2002, 67 FR 51289 (PDF).

Unapproved work

• FAQ. May the investigator begin animal work before receiving IACUC approval?

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, RealPlayer, Video or Flash files, see Help Downloading Files.