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Testing for Abuse Liability of Drugs in Humans |
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![]() NIDA Research Monograph, Number 92 [Printed in 1989]![]() Download Monograph92.pdf - Testing for Abuse Liability of Drugs in Humans (2.2 MB) Table of Contents Introduction Testing and Abuse Liability of Drugs in Humans-----1 The Necessity and Utility of Abuse Liability Evaluations in Human Subjects: The FDA Perspective-----7 The Role of Abuse Liability Testing in Drug Control Procedures-----21 Historical Perspectives on the Use of Subjective Effects Measures in Assessing the Abuse Potential of Drugs-----43 Drug Identification and Classification Human Abuse Liability Assessment by Measurement of Subjective and Physiological Effects-----73 Drug Discrimination: Methods for Drug Characterization and Classification-----101 Assessment of the Reinforcing Properties Abuse Liability of Anxiolytics and Sedative/Hypnotics: Methods Assessing the Likelihood of Abuse-----123 Drug Self-Administration Procedures: Alcohol and Marijuana-----147 The Use of Choice Procedures for Assessing the Reinforcing Properties of Drugs in Humans-----171 Relationship Between Self-Reported Drug Effects and Their Reinforcing Effects: Studies with Stimulant Drugs-----211 Epidemiologic Assessment of Drug Abuse of Drugs Case Reports and the Assessment of Drug Abuse Liability-----231 United States Epidemiologic Data on Drug Use and Abuse: How are They Relevant to Testing Abuse Liability of Drugs?-----241 Current Approaches to Measurements of Drug Use and Abuse in Sweden-----267 Evaluation of the Abuse Liability of Drugs in Humans: Issues and Future Directions Pharmacokinetic and Phartnacodynamic Drug Interactions: Implications for Abuse Liability Testing-----287 Promising New Biologic and Behavioral Correlates of the Reinforcing Properties of Drugs-----307 Drug Abuse Liability Testing: Human Subject Issues-----341 Issues in Human Drug Abuse Liability Testing: Overview and Prospects for the Future-----357 Conference Summary and Perspectives on Human Drug Abuse Liability Testing-----371 Index-----377 List of NIDA Research Monographs-----393 |
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