Hydrogenase Active Sites and the Origin of Life

April 6, 2009 / Posted by: Daniella Scalice

Members of NAI’s Team at Montana State University have provided a Perspectives piece in Dalton Transactions reviewing the organo-metallic chemistry of the active sites of hydrogenase enzymes. Since hydrogen metabolism is presumed to be an early feature in the energetics of life, and hydrogen metabolizing organisms can be traced very early in molecular phylogeny, studying the metal clusters at hydrogenase active sites can reveal potential conditions in which early life arose. Efforts in this field also could have significant impacts on alternative and renewable energy solutions.