Familial Cancer Syndromes Summary
Clinical Genetics Branch Chief, Dr. Mark H. Greene, and Genetic Epidemiology Branch
Staff Clinician, Dr. Mary Lou McMaster, have collaborated with Mayo Clinic colleague Dr.
Noralane Lindor, to produce the second edition of The Concise Handbook of
Familial Cancer Susceptibility Syndromes, published as a Journal of the National
Cancer Institute Monograph.
The first edition of this clinical cancer genetics resource was published more than 10
years ago, at which time it quickly became one of the most valuable and widely-used
information tools among health care professionals involved in the evaluation and
management of genetically at-risk persons and families.
The new edition expands the number of syndromes covered from 35 to 54. New modules
addressing the familial hematopoietic and lymphoproliferative disorders have been added as
well. The syndromes are listed in alphabetical order, and a templated capsule summary of
selected aspects of each disorder is provided.
One of the novel and most valuable features of the first edition, its tabular summary
of cancers associated with each syndrome, has been enhanced through the addition of two
new tables: "Benign Neoplasms" and "Non-Neoplastic Conditions" associated with each
syndrome.
